Related references
Note: Only part of the references are listed.Reduction of leukemic burden via bone-targeted nanoparticle delivery of an inhibitor of C-chemokine (C-C motif) ligand 3 (CCL3) signaling
Marian A. Ackun-Farmmer et al.
FASEB JOURNAL (2021)
The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis
Parimala Sonika Godavarthy et al.
HAEMATOLOGICA (2020)
Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance
Valerie Barbier et al.
NATURE COMMUNICATIONS (2020)
Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer
Yann Kieffer et al.
CANCER DISCOVERY (2020)
VEGF-C protects the integrity of the bone marrow perivascular niche in mice
Shentong Fang et al.
BLOOD (2020)
Targeting adhesion to the vascular niche to improve therapy for acute myeloid leukemia
Myriam L. R. Haltalli et al.
NATURE COMMUNICATIONS (2020)
Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection
Myriam L. R. Haltalli et al.
NATURE CELL BIOLOGY (2020)
Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2
Marcus A. Florez et al.
CELL REPORTS (2020)
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells
Puneet Agarwal et al.
CELL STEM CELL (2019)
Age-related inflammation triggers skeletal stem/progenitor cell dysfunction
Anne Marie Josephson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The Impact of Aging on Adipose Function and Adipokine Synthesis
Peter Mancuso et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
Ya-Hsuan Ho et al.
CELL STEM CELL (2019)
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress
Richard Burt et al.
BLOOD (2019)
Aged marrow macrophages expand platelet-biased hematopoietic stem cells via interleukin-1B
Benjamin J. Frisch et al.
JCI INSIGHT (2019)
Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion
B. Kumar et al.
LEUKEMIA (2018)
Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML
Delfim Duarte et al.
CELL STEM CELL (2018)
Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies
Robert L. Bowman et al.
CELL STEM CELL (2018)
Roles of the bone marrow niche in hematopoiesis, leukemogenesis, and chemotherapy resistance in acute myeloid leukemia
Andi Wang et al.
HEMATOLOGY (2018)
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia
Bin Zhang et al.
NATURE MEDICINE (2018)
Prediction of acute myeloid leukaemia risk in healthy individuals
Sagi Abelson et al.
NATURE (2018)
The Chemokine CCL3 Regulates Myeloid Differentiation and Hematopoietic Stem Cell Numbers
Rhonda J. Staversky et al.
SCIENTIFIC REPORTS (2018)
The microenvironment in myelodysplastic syndromes: Niche-mediated disease initiation and progression
Allison J. Li et al.
EXPERIMENTAL HEMATOLOGY (2017)
Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF
Bo O. Zhou et al.
NATURE CELL BIOLOGY (2017)
Differential cytokine contributions of perivascular haematopoietic stern cell niches
Noboru Asada et al.
NATURE CELL BIOLOGY (2017)
Foxp3+ regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis
Antonio Pierini et al.
NATURE COMMUNICATIONS (2017)
Pro-inflammatory-Related Loss of CXCL12 Niche Promotes Acute Lymphoblastic Leukemic Progression at the Expense of Normal Lymphopoiesis
Juan Carlos Balandran et al.
FRONTIERS IN IMMUNOLOGY (2017)
Multiple myeloma
Shaji K. Kumar et al.
NATURE REVIEWS DISEASE PRIMERS (2017)
Inflammation: a key regulator of hematopoietic stem cell fate in health and disease
Eric M. Pietras
BLOOD (2017)
Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration
Thomas H. Ambrosi et al.
CELL STEM CELL (2017)
Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome
Sophia R. Balderman et al.
BLOOD (2016)
MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice
Tomohisa Baba et al.
BLOOD (2016)
Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells
Kevin A. Goncalves et al.
CELL (2016)
Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia
Noemi A. Zambetti et al.
CELL STEM CELL (2016)
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner
Yahya S. Al-Matary et al.
HAEMATOLOGICA (2016)
Mouse models for radiation-induced cancers
Leena Rivina et al.
MUTAGENESIS (2016)
T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments
Edwin D. Hawkins et al.
NATURE (2016)
Distinct bone marrow blood vessels differentially regulate haematopoiesis
Tomer Itkin et al.
NATURE (2016)
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment
Lei Dong et al.
NATURE (2016)
Age-dependent modulation of vascular niches for haematopoietic stem cells
Anjali P. Kusumbe et al.
NATURE (2016)
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal
Eric M. Pietras et al.
NATURE CELL BIOLOGY (2016)
A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells
Andreas Reinisch et al.
NATURE MEDICINE (2016)
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner
Yahya S. Al-Matary et al.
HAEMATOLOGICA (2016)
Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development
Marisa Bowers et al.
BLOOD (2015)
From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation
Tarik Moeroey et al.
BLOOD (2015)
CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance
Lauren A. Pitt et al.
CANCER CELL (2015)
Myelosuppressive Therapies Significantly Increase ProInflammatory Cytokines and Directly Cause Bone Loss
Julie M. Quach et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2015)
Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal
Melih Acar et al.
NATURE (2015)
Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance
Rodrigo Jacamo et al.
BLOOD (2014)
Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow
Bo O. Zhou et al.
CELL STEM CELL (2014)
Acute Myelogenous Leukemia-Induced Sympathetic Neuropathy Promotes Malignancy in an Altered Hematopoietic Stem Cell Niche
Maher Hanoun et al.
CELL STEM CELL (2014)
Myelodysplastic Cells in Patients Reprogram Mesenchymal Stromal Cells to Establish a Transplantable Stem Cell Niche Disease Unit
Hind Medyouf et al.
CELL STEM CELL (2014)
Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity
Yuki Kagoya et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies
M. A. Frassanito et al.
LEUKEMIA (2014)
Direct measurement of local oxygen concentration in the bone marrow of live animals
Joel A. Spencer et al.
NATURE (2014)
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
Lorena Arranz et al.
NATURE (2014)
Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
Aruna Kode et al.
NATURE (2014)
Chronic variable stress activates hematopoietic stem cells
Timo Heidt et al.
NATURE MEDICINE (2014)
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion
Ingmar Bruns et al.
NATURE MEDICINE (2014)
Nichotherapy for stem cells: There goes the neighborhood
Jean-Pierre Levesque et al.
BIOESSAYS (2013)
Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation
Paolo Gallipoli et al.
BLOOD (2013)
Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance
Maria Casanova-Acebes et al.
CELL (2013)
Deciphering Hematopoietic Stem Cells in Their Niches: A Critical Appraisal of Genetic Models, Lineage Tracing, and Imaging Strategies
Chacko Joseph et al.
CELL STEM CELL (2013)
Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche
Koen Schepers et al.
CELL STEM CELL (2013)
Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ
Christian Schuerch et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia
Tomohisa Baba et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Trends in chronic myeloid leukemia incidence and survival in the United States from 1975 to 2009
Yiming Chen et al.
LEUKEMIA & LYMPHOMA (2013)
CXCL12 in early mesenchymal progenitors is. required for haematopoietic stem-cell maintenance
Adam Greenbaum et al.
NATURE (2013)
Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
Lei Ding et al.
NATURE (2013)
Arteriolar niches maintain haematopoietic stem cell quiescence
Yuya Kunisaki et al.
NATURE (2013)
CD169+ macrophages provide a niche promoting erythropoiesis under homeostasis and stress
Andrew Chow et al.
NATURE MEDICINE (2013)
Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia
Benjamin J. Frisch et al.
BLOOD (2012)
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
Aysegul V. Ergen et al.
BLOOD (2012)
Demand-adapted regulation of early hematopoiesis in infection and inflammation
Hitoshi Takizawa et al.
BLOOD (2012)
Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia
Bin Zhang et al.
CANCER CELL (2012)
Bone marrow and the control of immunity
Ende Zhao et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2012)
Endothelial and perivascular cells maintain haematopoietic stem cells
Lei Ding et al.
NATURE (2012)
Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow
Aya Ludin et al.
NATURE IMMUNOLOGY (2012)
Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation?
Celalettin Ustun et al.
BLOOD (2011)
IL-6 Controls Leukemic Multipotent Progenitor Cell Fate and Contributes to Chronic Myelogenous Leukemia Development
Damien Reynaud et al.
CANCER CELL (2011)
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
Satoshi Yamazaki et al.
CELL (2011)
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
Andrew Chow et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
Joji Fujisaki et al.
NATURE (2011)
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
Ingrid G. Winkler et al.
BLOOD (2010)
Age at Diagnosis and the Utility of Prognostic Testing in Patients With Chronic Lymphocytic Leukemia
Tait D. Shanafelt et al.
CANCER (2010)
Gfi1 and Gfi1b: key regulators of hematopoiesis
L. T. van der Meer et al.
LEUKEMIA (2010)
Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
Megan T. Baldridge et al.
NATURE (2010)
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
Marc H. G. P. Raaijmakers et al.
NATURE (2010)
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
Simon Mendez-Ferrer et al.
NATURE (2010)
Patterns of Multiple Myeloma During the Past 5 Decades: Stable Incidence Rates for All Age Groups in the Population but Rapidly Changing Age Distribution in the Clinic
Ingemar Turesson et al.
MAYO CLINIC PROCEEDINGS (2010)
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
Cristina Lo Celso et al.
NATURE (2009)
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
Olaia Naveiras et al.
NATURE (2009)
IFNα activates dormant haematopoietic stem cells in vivo
Marieke A. G. Essers et al.
NATURE (2009)
Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion
Taku Sato et al.
NATURE MEDICINE (2009)
Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblasts
Shuanhu Zhou et al.
AGING CELL (2008)
Defective Notch activation in microenvironment leads to myeloproliferative disease
Young-Woong Kim et al.
BLOOD (2008)
Haematopoietic stem cell release is regulated by circadian oscillations
Simon Mendez-Ferrer et al.
NATURE (2008)
The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress
Deidre Daria et al.
BLOOD (2008)
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
Fumihiko Ishikawa et al.
NATURE BIOTECHNOLOGY (2007)
Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
Benedetto Sacchetti et al.
CELL (2007)
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
Stuart M. Chambers et al.
PLOS BIOLOGY (2007)
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment
Carl R. Walkley et al.
CELL (2007)
A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor γ deficiency
Carl R. Walkley et al.
CELL (2007)
Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells
Jiang Zhu et al.
BLOOD (2007)
Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
Tatsuki Sugiyama et al.
IMMUNITY (2006)
Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in ostcoblastic cells
Jonathan M. Weber et al.
BONE (2006)
Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cells
Carl R. Walkley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells
LB Yao et al.
BLOOD (2005)
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
MJ Kiel et al.
CELL (2005)
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
F Arai et al.
CELL (2004)
Osteoblastic cells regulate the haematopoietic stem cell niche
LM Calvi et al.
NATURE (2003)
Identification of the haematopoietic stem cell niche and control of the niche size
JW Zhang et al.
NATURE (2003)
Stem cells, cancer, and cancer stem cells
T Reya et al.
NATURE (2001)
Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia
JJ Molldrem et al.
NATURE MEDICINE (2000)