Advances in Organophosphorus Redox Catalysis

Organophosphorus reagents play very important role in organic synthesis. The development of Wittig reaction, Staudinger reaction, Appel reaction and Mitsunobu reaction mediated by phosphine compounds is of great significance in scientific research and industrial production. In recent decades, the research on the design of P(III)/P(V) redox catalysis and catalysts to realize the catalytic mode of these reactions, and avoiding the production of stoichiometric R3P=O has developed rapidly. This review introduces the research progress of the catalytic process of each reaction in turn. The future research direction in this field about the reactions involving stoichiometric R3P=O is prospected.

Automated summary

This review introduces the research progress of the catalytic process of Wittig reaction, Staudinger reaction, Appel reaction, and Mitsunobu reaction mediated by phosphine compounds, and points out that the future research direction is to avoid the production of stoichiometric R3P=O.