4.6 Article

Common Shortcomings in Study on Radiopharmaceutical Design Research: A Case Study of 99mTc-Labelled Methotrexate

Journal

MOLECULES
Volume 26, Issue 19, Pages -

Publisher

MDPI
DOI: 10.3390/molecules26195862

Keywords

methotrexate; radiopharmaceuticals; technetium-99m

Funding

  1. International Atomic Energy Agency (IAEA) [22521]
  2. Ministry of Science and Higher Education [3882/IAEA/2018/0]

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The aim of this work is to address the shortcomings often seen in the design of new radiopharmaceuticals, as highlighted by a case study on Tc-99m-labelled methotrexate. The article points out common mistakes and misconceptions in radiopharmaceutical studies and emphasizes the importance of credibility in scientific research for reliable results.
The aim of the work carried out was to draw attention to shortcomings that often appear at the stage of designing new radiopharmaceuticals. Based on a case study of Tc-99m-labelled methotrexate, this article describes frequent mistakes or misconceptions present not only in the referenced studies, but also in numerous radiopharmaceutical studies. The recommendations provided in this article highlight fundamental aspects of the credibility of radiopharmaceutical scientific research leading to the reliable results.

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