Calix[n]triazolium based turn-on fluorescent sensing ensemble for selective adenosine monophosphate (AMP) detection

A novel calix[n]triazolium was synthesized and exhibited excellent selectivity for AMP. The binding between calix[n]triazolium and chromenolate anions forms a non-fluorescent complex and the resulting supramolecular ensemble selectively detects AMP in water and induces turn-on fluorescence. The sensing platform is the first macrocyclic system to discriminate AMP from ADP and ATP through fluorescence changes.

Automated summary

A novel calix[n]triazolium was synthesized, which showed excellent selectivity for detecting AMP through turn-on fluorescence. This macrocyclic system is the first to discriminate AMP from ADP and ATP based on fluorescence changes.