Journal
ANALYTICAL METHODS
Volume 13, Issue 45, Pages 5509-5515Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ay01635k
Keywords
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Funding
- National Natural Science Foundation of China [NSFC 61805005]
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This paper investigates the application of CdTeSe/ZnS core-shell quantum dots (QDs) in cancer treatment. The QDs were prepared by aqueous synthesis and showed great potential in biomedical imaging and biological ablation therapy. The study provides a new research direction and method for cancer treatment.
Micro targeted therapy for cancer has become a hot topic in recent years because of its advantages of little damage to the human body and early treatment of cancer. Therefore, accurate, rapid treatment methods and biofriendly exogenous substances are extremely important. CdTeSe/ZnS core-shell quantum dots (QDs) have great potential in biomedical imaging and biological ablation therapy due to their advantages of near-infrared radiation, aqueous synthesis and bio-friendliness. In this paper, CdTeSe/ZnS core-shell QDs were prepared by aqueous synthesis, and have near infrared output and excellent photothermal properties. A blue laser was used as the irradiation source and QD fluorescence imaging can accurately calibrate the treatment area. Under the photothermal and photodynamic effects of QDs, apoptosis of hepatoma cells Huh7 was induced, which provides a new micro-nano technology and biofriendly exogenous substances for cancer treatment.
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