Journal
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
Volume 27, Issue 3, Pages 267-277Publisher
SPRINGER
DOI: 10.1007/s00787-017-1045-4
Keywords
ADHD; Headache; Migraine; Tension-type headache; Meta-analysis; Stimulants
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An association between primary headaches and attention-deficit/hyperactivity disorder (ADHD) has long been suggested. Moreover, headache is regarded as a common side effect of stimulants, the most effective treatment for ADHD. So far, no systematic review has evaluated the potential association between ADHD and headache. We performed a systematic review of the literature and a meta-analysis of all reported studies on ADHD and primary headaches. Our analysis showed a positive association between ADHD and migraine (OR 1.322, 95% CI 1.018-1717, p value 0.036), but not with tension-type headache. There is a significant association between migraine and ADHD. The mechanisms underlying this association remain to be elucidated, warranting further studies.
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