Journal
HETEROCYCLES
Volume 102, Issue 8, Pages 1579-1587Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-21-14482
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Funding
- National Natural Foundation of China [21807089]
- Special Fundamental Research Fund for the Central Public Scientific Research Institutes [562018Y-5983]
- Science and Technology Program of China State Administration for Market Regulation [2019MK117]
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Two new diterpenoid alkaloids and eight known ones were isolated from the root of Aconitum leucostomum. Compound 2 showed antifeedant activity with an effective concentration for 50% feeding reduction (EC50) at 1.54 mg/cm(2).
Two new diterpenoid alkaloids and eight known ones were isolated from the root of Aconitum leucostomum. Their structures were elucidated on the basis of extensive spectroscopic analyses such as HR-ESI-MS, 1D NMR and 2D NMR spectra. Compounds 1, 2, 5, 6 and 8 were tested for their antifeedant activity against Spodoptera exigua Hubner, and compound 2 showed antifeedant activity with an effective concentration for 50% feeding reduction (EC50) at 1.54 mg/cm(2).
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