Journal
IEEE OPEN JOURNAL OF NANOTECHNOLOGY
Volume 2, Issue -, Pages 86-100Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/OJNANO.2021.3119913
Keywords
DNA; Nanostructures; Shape; Tools; Rigidity; Three-dimensional displays; Self-assembly; DNA; nanotechnology; design principle; computational tools
Funding
- National Research Foundation (NRF) of Korea - Ministry of Science and ICT [NRF-2020M3F7A1094299, NRF-2019R1A2C4069541, NRF-2020R1I1A1A01071567, NRF-2021R1C1C2003554]
- National Research Foundation (NRF) of Korea - Ministry of Education [NRF-2020M3F7A1094299, NRF-2019R1A2C4069541, NRF-2020R1I1A1A01071567, NRF-2021R1C1C2003554]
- National Institute of Health (NIH) [HG010055]
- Center for Advanced Surface Engineering (CASE) under National Science Foundation (NSF) [OIA-1457888]
- Arkansas EPSCoR Program
- ASSET III
- Arkansas Biosciences Institute
- KAKENHI - Ministry of Education, Culture, Sports, Science and Technology (MEXT) [16H03841, 19H02571]
- Grants-in-Aid for Scientific Research [16H03841, 19H02571] Funding Source: KAKEN
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Structural DNA nanotechnology enables the design of nanoscale structures with desired shape and properties through evolved design strategies and computational tools, allowing for fine control over both shape and physicochemical properties of the structure.
Designing a structure in nanoscale with desired shape and properties has been enabled by structural DNA nanotechnology. Design strategies in this research field have evolved to interpret various aspects of increasingly more complex nanoscale assembly and to realize molecular-level functionality by exploring static to dynamic characteristics of the target structure. Computational tools have naturally been of significant interest as they are essential to achieve a fine control over both shape and physicochemical properties of the structure. Here, we review the basic design principles of structural DNA nanotechnology together with its computational analysis and design tools.
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