Fluorescent detection of decamethoxine by reaction with eosin Y in medicines

The influence of cationic, anionic, and nonionic surfactant solutions on the nature of the fluorescence spectra of reagents of different charges and hydrophobicity in aqueous solutions has been studied. The increase in the surfactant analytical signal with increasing contribution of the role of electrostatic interactions between the reagent particle and ionic surfactant has been shown. The observed effect is explained by the implementation of charge matching in the interaction of surfactants with the reagents. Hydrophobic binding of oppositely charged reagent particles and surfactants further enhances the effect of charge matching. The elimination of the detected effect for reagents that exhibit weak solvatochromic properties has been shown. The conditions for detecting the content of hydrophobic organic substances of cationic nature by reaction with eosin Y have been proposed.

Automated summary

The study found that charge matching plays an important role in the interaction between ionic surfactants and reagents, enhancing the analytical signal of the surfactants. Additionally, hydrophobic binding between oppositely charged reagent particles and surfactants can further enhance the effect of charge matching, while the detection effect is not significant for reagents with weak solvatochromic properties.