Journal
POLYMER SCIENCE SERIES C
Volume 63, Issue 2, Pages 199-218Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1811238221020107
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Funding
- Russian Science Foundation [18-29-17016]
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This review discusses the physicochemical basis and structural and morphological opportunities of various methods for the manufacture of porous polylactide. It emphasizes the effect of porous structure parameters on the rate of hydrolytic degradation of the polymer and the prospects for the development of application areas of similar porous materials in biomedicine.
Polylactide-based materials are often considered an alternative to materials produced from traditionally hardly degradable polymers. Porous polylactide membranes, matrices, and scaffolds are especially attractive for use in biomedicine. The review concerns the physicochemical basis and structural and morphological opportunities of various methods for the manufacture of porous polylactide, such as sintering, 3D printing, electrospinning, foaming, etching, and the processes of phase separation and orientational drawing. Special attention is focused on the effect of porous structure parameters on the rate of hydrolytic degradation of the polymer and the prospects for the development of application areas of similar porous materials.
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