SYNTHETIC APPROACHES TOWARD CERTAIN STRUCTURALLY RELATED ANTIMICROBIAL THIAZOLE DERIVATIVES (2010-2020)

In the present literature review, we comprehensively discuss different methods of synthesis of published antimicrobial thiazole derivatives in the last decade mainly those which showed antibacterial, antimycobacterial and/or antifungal activity. Owing to the great diversity of thiazole-derived antimicrobial agents, we organized most of them chemically in stipulated classes. In each class, we mentioned common methods of thiazole ring closure and indicated antimicrobial activity of the most active derivatives in clear and simple way.

Automated summary

In this literature review, various methods of synthesizing antimicrobial thiazole derivatives published in the past decade are comprehensively discussed, with a focus on those exhibiting antibacterial, antimycobacterial, and/or antifungal activity. The diversity of thiazole-derived antimicrobial agents is highlighted through categorization into chemical classes, showcasing the common methods of thiazole ring closure and the antimicrobial activity of the most potent derivatives.