Journal
KOREAN JOURNAL OF RADIOLOGY
Volume 22, Issue 11, Pages 1858-1874Publisher
KOREAN RADIOLOGICAL SOC
DOI: 10.3348/kjr.2020.1450
Keywords
CNS tumor; Molecular marker; Magnetic resonance imaging; Positron emission tomography
Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, Information and Communication Technologies & Future Planning [2020R1A2C1003886]
- National Research Foundation of Korea [2020R1A2C1003886] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Advances in molecular and genetic characterization of CNS tumors have led to a new era of tumor classification and imaging plays a critical role in preoperative diagnosis, surgical planning, molecular marker prediction, targeted treatment planning, and post-therapy assessment.
Recent advances in the molecular and genetic characterization of central nervous system (CNS) tumors have ushered in a new era of tumor classification, diagnosis, and prognostic assessment. In this emerging and rapidly evolving molecular genetic era, imaging plays a critical role in the preoperative diagnosis and surgical planning, molecular marker prediction, targeted treatment planning, and post-therapy assessment of CNS tumors. This review provides an overview of the current imaging methods relevant to the molecular genetic classification of CNS tumors. Specifically, we focused on 1) the correlates between imaging features and specific molecular genetic markers and 2) the post-therapy imaging used for therapeutic assessment.
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