Denaturation of the SARS-CoV-2 spike protein under non-thermal microwave radiation

Editorial Material Medicine, General & Internal

Oxford-AstraZeneca COVID-19 vaccine efficacy

Maria Deloria Knoll et al.

LANCET (2021)

Letter Medicine, General & Internal

New SARS-CoV-2 Variants - Clinical, Public Health, and Vaccine Implications

Salim S. Abdool Karim et al.

Summary: The emergence of SARS-CoV-2 variants, including B.1.1.7 (VOC-202012/01), 501Y.V2 (B.1.351), and P.1 (B.1.1.28.1), has raised concerns about worsening Covid-19 and potential escape from vaccine-induced immunity.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Review Microbiology

SARS-CoV-2 variants, spike mutations and immune escape

William T. Harvey et al.

Summary: The evolution of SARS-CoV-2 has been characterized by the emergence of mutations and variants that impact virus characteristics. Manufacturers are preparing for possible updates to vaccines in response to changes in the virus population, and it is crucial to monitor genetic and antigenic changes alongside experiments to understand the impacts of mutations.

NATURE REVIEWS MICROBIOLOGY (2021)

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Article Biochemistry & Molecular Biology

Temperature effect on the SARS-CoV-2: A molecular dynamics study of the spike homotrimeric glycoprotein

Didac Marti et al.

Summary: Heating has been shown to inactivate the SARS-CoV-2 virus, with the exposure time for total inactivation depending on the reached temperature. Molecular dynamics simulations revealed significant changes in the topology of hydrogen bonding interactions and secondary structure of the receptor binding domain of the spike protein at different temperatures. The proposed inactivation mechanism suggests potential new approaches to combat the SARS-CoV-2 coronavirus.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2021)

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Review Multidisciplinary Sciences

Percutaneous microwave ablation applications for liver tumors: recommendations for COVID-19 patients

Pooya Afaghi et al.

Summary: Microwave ablation (MWA) is a safe and effective method for treating tumors, with higher completion rates for smaller tumors. Different frequencies, specifically 915 MHz and 2.45 GHz, may be more effective for ablating large tumors. Liver function tests are recommended for COVID-19 patients with hepatic tumors undergoing MWA to monitor potential liver injury.

HELIYON (2021)

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Letter Immunology