☆ 4.7 Article

A cooperative Pd/Co catalysis system for the asymmetric (4+2) cycloaddition of vinyl benzoxazinones with N-acylpyrazoles

CHEMICAL COMMUNICATIONS (2021)

Related references

Note: Only part of the references are listed.

Article Chemistry, Multidisciplinary

Synergistic Catalysis with Azomethine Ylides

Liang Wei et al.

Summary: Azomethine ylides are important intermediates for the construction of chiral N-containing compounds. Through synergistic catalysis and azomethine ylide chemistry, novel catalytic systems have been developed to convert readily available azomethine ylides into high-valued molecules. The synergistic catalyst system shows enhanced catalytic efficiency and chiral induction ability compared to traditional mono-catalysis, and can be applied in the synthesis of bioactive compounds and natural products.

CHINESE JOURNAL OF CHEMISTRY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Stereodivergent Synthesis of Enantioenriched γ-Butyrolactones Bearing Two Vicinal Stereocenters Enabled by Synergistic Copper and Iridium Catalysis

Lu Xiao et al.

Summary: Utilizing a new reaction model, gamma-butyrolactones with diverse stereoisomers were prepared stereospecifically through a synergistic Cu/Ir-catalyzed asymmetric cascade reaction, allowing control of vicinal stereocenters. The study of the chiral intermediate shed light on the regio- and stereoselectivity of the initial bond formation process, while control experiments provided insight into catalyst interactions in the dual catalytic system. Enantioenriched products were further converted into structurally complex chiral molecules and organocatalysts, expanding the synthetic accessibility of these compounds.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Diastereodivergent Synthesis of β-Amino Alcohols by Dual-Metal-Catalyzed Coupling of Alkoxyallenes with Aldimine Esters

Minghui Zhu et al.

Summary: The study presents a dual-metal catalyzed diastereodivergent coupling method for the synthesis of beta-amino alcohols with multiple stereoisomers, enabling the concise preparation of natural products such as mycestericins F and G.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Asymmetric Synthesis of Hydroquinolines with α,α-Disubstitution through Organocatalyzed Kinetic Resolution

Yunrong Chen et al.

Summary: The first kinetic resolution of hydroquinoline derivatives with alpha,alpha-disubstitution has been achieved through asymmetric remote aminations with azodicarboxylates enabled by chiral phosphoric acid catalysis. Mechanistic studies suggest a monomeric catalyst pathway proceeding through rate- and enantio-determining electrophilic attack promoted by a network of attractive non-covalent interactions between the substrate and catalyst. Facile subsequent removal and transformations of the newly introduced hydrazine moiety enable these protocols to serve as powerful tools for asymmetric synthesis of N-heterocycles with alpha,alpha-disubstitution.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Manganese-Catalyzed Asymmetric Hydrogenation of Quinolines Enabled by π-π Interaction

Chenguang Liu et al.

Summary: The article reports on the non-noble metal-catalyzed asymmetric hydrogenation of N-heteroaromatics, quinolines. A new chiral pincer manganese catalyst showed outstanding catalytic activity in the reaction, producing high yields and enantioselectivities. The precise regulation of enantioselectivity was ensured by a pi-pi interaction, achieving competitive turnover numbers with noble metal catalysts.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Stereodivergent Synthesis of Tertiary Fluoride-Tethered Allenes via Copper and Palladium Dual Catalysis

Shao-Qian Yang et al.

Summary: The protocol describes the unprecedented stereodivergent synthesis of tertiary fluoride-tethered allenes with a stereogenic center and stereogenic axis via Cu/Pd synergistic catalysis. A wide range of conjugated enynes are coupled with various alpha-fluoroesters in high yields and diastereoselectivity. The novel stereodivergent axial-to-central chirality transfer process enables precise access to the corresponding four stereoisomers of fluorinated hydrofurans.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Enantio- and Diastereodivergent Synthesis of Spirocycles through Dual-Metal-Catalyzed [3+2] Annulation of 2-Vinyloxiranes with Nucleophilic Dipoles

Youbin Peng et al.

Summary: This study presents an enantio- and diastereodivergent synthesis of rigid spirocycles through dual-metal catalysis, offering a promising approach for the development of new N-olefin ligands. Preliminary mechanistic studies were conducted to understand the bimetallic catalysis process.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis

Jiacheng Zhang et al.

Summary: This study presents a method for the construction of 1,3-nonadjacent stereocenters through Pd/Cu-catalyzed asymmetric synthesis, providing highly enantio- and diastereoselective chiral products; The protocol is applicable to a wide range of substrates, including challenging allenylic esters with less sterically bulky substituents; Moreover, various transformations involving axial-to-central chirality transfer were conducted, yielding useful structural motifs containing nonadjacent stereocenters in a diastereodivergent manner.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Multidisciplinary Sciences

Practical iridium-catalyzed direct α-arylation of N-heteroarenes with (hetero)arylboronic acids by H2O-mediated H2 evolution

Liang Cao et al.

Summary: 2-(hetero)aryl N-heteroarenes are widely used in various fields but lack a general synthetic method. The authors present an iridium(III)-catalyzed approach for direct alpha-arylation of N-heteroarenes with aryl and heteroaryl boronic acids, using a H2O-mediated H-2-evolution cross-coupling strategy, providing a practical route for direct access to these compounds.

NATURE COMMUNICATIONS (2021)

Add to Collection

Article Chemistry, Physical

Gold-Catalyzed Skeletal Rearrangement of Alkenes: Regioselective Synthesis of Skeletally Diverse Tricyclic Heterocycles and Mechanistic Investigations

Xiao-Yan Qin et al.

Summary: Transition metal-catalyzed skeletal rearrangement reactions have rapidly advanced in the organic community, providing versatile methods for selective synthesis of special molecular scaffolds. A gold-catalyzed skeletal rearrangement of alkenes with alkynyl bromides was reported in this study, allowing for the regioselective generation of diverse tricyclic heterocycles with good yields. Mechanistic investigations using theoretical calculations were conducted to explain the regioselectivity of the reaction.

ACS CATALYSIS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Synergistic Cu/Pd-catalyzed asymmetric allylation: a facile access to α-quaternary cysteine derivatives

Hui-Min Wu et al.

Summary: An efficient synthetic methodology was developed to access biologically important and synthetically useful alpha-quaternary cysteine derivatives via asymmetric catalytic alpha-allylation. A wide array of alpha-quaternary cysteine derivatives were obtained with good to excellent enantioselectivities, and gram-scale asymmetric allylation was performed to maintain high yields. Additionally, synthetic transformations to access chiral spirocyclic compounds proceeded smoothly, demonstrating the utility of this methodology.

CHEMICAL COMMUNICATIONS (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Synergistic Pd/Cu Catalysis in Organic Synthesis

Yue Wu et al.

CHEMISTRY-A EUROPEAN JOURNAL (2020)

Add to Collection

Article Chemistry, Physical

Diastereodivergent synthesis of enantioenriched alpha,beta-disubstituted gamma-butyrolactones via cooperative N-heterocyclic carbene and Ir catalysis

Santanu Singha et al.

NATURE CATALYSIS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Palladium-Catalyzed Asymmetric [8+2] Dipolar Cycloadditions of Vinyl Carbamates and Photogenerated Ketenes

Qun-Liang Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Article Chemistry, Physical

NHC-Catalyzed 1,2-Selective Hydroboration of Quinolines

Jinseong Jeong et al.

ACS CATALYSIS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Utilizing Vinylcyclopropane Reactivity: Palladium-Catalyzed Asymmetric [5+2] Dipolar Cycloadditions

Miao-Miao Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Synergistic Dual Transition Metal Catalysis

U. Bin Kim et al.

CHEMICAL REVIEWS (2020)

Add to Collection

Article Chemistry, Organic

Enantioselective Synthesis of Multisubstituted Spirocyclopentane Oxindoles Enabled by Pd/Chiral Rh(III) Complex Synergistic Catalysis

Qian Wan et al.

ORGANIC LETTERS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Nucleophilic Dearomatization of N-Heteroaromatics Enabled by Lewis Acids and Copper Catalysis

Xingchen Yan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Inverse-Electron-Demand Palladium-Catalyzed Asymmetric [4+2] Cycloadditions Enabled by Chiral P,S-Ligand and Hydrogen Bonding

Ya-Ni Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Add to Collection

Review Chemistry, Multidisciplinary

Progress in the Chemistry of Tetrahydroquinolines

Isravel Muthukrishnan et al.

CHEMICAL REVIEWS (2019)

Add to Collection

Article Chemistry, Organic

Rh(II)-Catalyzed Highly Diastereoselective Cascade Transannulation of N-Sulfonyl-1,2,3-triazoles and Vinyl Benzoxazinanones

Kuntal Pal et al.

ORGANIC LETTERS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Exploration of a Chiral Cobalt Catalyst for Visible-Light-Induced Enantioselective Radical Conjugate Addition

Kai Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Stereodivergent Construction of Tertiary Fluorides in Vicinal Stereogenic Pairs by Allylic Substitution with Iridium and Copper Catalysts

Zhi-Tao He et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection

Article Multidisciplinary Sciences

Synergetic iridium and amine catalysis enables asymmetric [4+2] cycloadditions of vinyl aminoalcohols with carbonyls

Mao-Mao Zhang et al.

NATURE COMMUNICATIONS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Stereodivergent Coupling of 1,3-Dienes with Aldimine Esters Enabled by Synergistic Pd and Cu Catalysis

Qinglong Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioselective Trapping of Pd-Containing 1,5-Dipoles by Photogenerated Ketenes: Access to 7-Membered Lactones Bearing Chiral Quaternary Stereocenters

Yi Wei et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Iridium and a Bronsted acid cooperatively catalyzed chemodivergent and stereoselective reactions of vinyl benzoxazinones with azlactones

Meng Sun et al.

CHEMICAL COMMUNICATIONS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Stereodivergent Synthesis of α,α-Disubstituted α-Amino Acids via Synergistic Cu/Ir Catalysis

Liang Wei et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Stereodivergent Allylation of Azaaryl Acetamides and Acetates by Synergistic Iridium and Copper Catalysis

Xingyu Jiang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access to alpha,alpha-Disubstituted alpha-Amino Acids Bearing Vicinal Stereocenters

Xiaohong Huo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Article Chemistry, Organic

Transition-metal-catalyzed cyclization reactions using vinyl and ethynyl benzoxazinones as dipole precursors

Tian-Ren Li et al.

TETRAHEDRON LETTERS (2018)

Add to Collection

Review Chemistry, Multidisciplinary

Advances on Asymmetric Allylic Substitutions under Synergetic Catalysis System with Transition Metals and Organocatalysts

Zhang Mao-Mao et al.

ACTA CHIMICA SINICA (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis

Xiaohong Huo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Sequential Visible-Light Photoactivation and Palladium Catalysis Enabling Enantioselective [4+2] Cycloadditions

yiao-Miao Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Add to Collection

Review Chemistry, Organic

Cooperative bimetallic catalysis in asymmetric allylic substitution

Jingke Fu et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2017)

Add to Collection

Article Chemistry, Organic

Ir/Zn Dual Catalysis: Enantioselective and Diastereodivergent α-Allylation of Unprotected α-Hydroxy Indanones

Rui He et al.

ORGANIC LETTERS (2017)

Add to Collection

Article Chemistry, Organic

Catalytic Asymmetric Construction of the Tryptanthrin Skeleton via an Enantioselective Decarboxylative [4+2] Cyclization

Guang-Jian Mei et al.

ORGANIC LETTERS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Synergistic Cu/Pd Catalysis for Enantioselective Allylic Alkylation of Aldimine Esters: Access to ,-Disubstituted -Amino Acids

Liang Wei et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Add to Collection

Article Chemistry, Multidisciplinary

A catalytic asymmetric construction of a tetrahydroquinoline-based spirooxindole framework via a diastereo- and enantioselective decarboxylative [4+2] cycloaddition

Guang-Jian Mei et al.

CHEMICAL COMMUNICATIONS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

P,SLigands for the Asymmetric Construction of Quaternary Stereocenters in Palladium-Catalyzed Decarboxylative [4+2] Cycloadditions

Yi Wei et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Iron-Catalyzed Decarboxylative (4+1) Cycloadditions: Exploiting the Reactivity of Ambident Iron-Stabilized Intermediates

Qiang Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Decarboxylative [4+2] Cycloaddition by Synergistic Palladium and Organocatalysis

Lars A. Leth et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Add to Collection

Article Chemistry, Multidisciplinary

An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones

Xiaohong Huo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations

Chang Guo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Catalytic Asymmetric [4+1] Annulation of Sulfur Ylides with Copper-Allenylidene Intermediates

Qiang Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Add to Collection

Article Multidisciplinary Sciences

Asymmetric trapping of zwitterionic intermediates by sulphur ylides in a palladium-catalysed decarboxylation-cycloaddition sequence

Tian-Ren Li et al.

NATURE COMMUNICATIONS (2014)

Add to Collection

Review Chemistry, Multidisciplinary

Cooperative bimetallic catalysis in asymmetric transformations

Jongwoo Park et al.

CHEMICAL SOCIETY REVIEWS (2012)

Add to Collection

Article Chemistry, Multidisciplinary

Synergistic catalysis: A powerful synthetic strategy for new reaction development

Anna E. Allen et al.

CHEMICAL SCIENCE (2012)

Add to Collection

Review Chemistry, Multidisciplinary

Advances in the Chemistry of Tetrahydroquinolines

Vellaisamy Sridharan et al.

CHEMICAL REVIEWS (2011)

Add to Collection

Article Chemistry, Multidisciplinary

Asymmetric cycloadditions of palladium-polarized aza-o-xylylenes

Chao Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Add to Collection

Article Chemistry, Multidisciplinary

Cooperative dual catalysis: Application to the highly enantioselective conjugate cyanation of unsaturated imides

GM Sammis et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.