Journal
JOURNAL OF OSTEOPATHIC MEDICINE
Volume 121, Issue 12, Pages 899-904Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1515/jom-2021-0129
Keywords
atypical diabetes; latent autoimmune diabetes of the adult; monogenic diabetes; secondary diabetes
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Diabetes mellitus is a complex disease that can have many different types, and atypical forms of diabetes can mimic type 1 or type 2 diabetes, making accurate diagnosis important for optimizing treatment.
Diabetes mellitus is a complex set of conditions that impacts 34 million Americans. While type 1 diabetes, type 2 diabetes, and gestational diabetes are most frequently encountered, there are many other types of diabetes with which healthcare providers are less familiar. These atypical forms of diabetes make up nearly 10% of diabetes cases and can masquerade as type 1 or 2 diabetes mellitus (T1DM or T2DM), and the treatment may not be optimized if the diagnosis is not accurate. Atypical forms include monogenic diabetes (formally known as maturity-onset diabetes of the young [MODY]), latent autoimmune diabetes of the adult (LADA), ketosis-prone diabetes, and secondary diabetes. This paper will detail the defining characteristics of each atypical form and demonstrate how they can masquerade as type 1 or 2 diabetes mellitus. Gestational diabetes mellitus will not be discussed in this article.
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