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EMBO JOURNAL (2010)
CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development
Julie Zikherman et al.
IMMUNITY (2010)
Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways
Keunwook Lee et al.
IMMUNITY (2010)
The power and the promise of restimulation-induced cell death in human immune diseases
Andrew L. Snow et al.
IMMUNOLOGICAL REVIEWS (2010)
Direct Observation and Quantitative Analysis of Lck Exchange between Plasma Membrane and Cytosol in Living T Cells
Lars Zimmermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Distinctive CD3 Heterodimeric Ectodomain Topologies Maximize Antigen-Triggered Activation of αβ T Cell Receptors
Sun Taek Kim et al.
JOURNAL OF IMMUNOLOGY (2010)
Biochemical and Genetic Evidence for a SAP-PKC-θ Interaction Contributing to IL-4 Regulation
Jennifer L. Cannons et al.
JOURNAL OF IMMUNOLOGY (2010)
An Alternative Conformation of the T-Cell Receptor a Constant Region
Gijs I. van Boxel et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Myristoylation and Membrane Binding Regulate c-Src Stability and Kinase Activity
Parag Patwardhan et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
T Cell Specific Adapter Protein (TSAd) Interacts with Tec Kinase ITK to Promote CXCL12 Induced Migration of Human and Murine T Cells
Tone Berge et al.
PLOS ONE (2010)
The adapter protein Nck: Role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes
Marcus Lettau et al.
PROTEIN SCIENCE (2010)
Oncogenic Activation of NF-kappa B
Louis M. Staudt
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
ZAP-70: An Essential Kinase in T-cell Signaling
Haopeng Wang et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Structural Biology of the T-cell Receptor: Insights into Receptor Assembly, Ligand Recognition, and Initiation of Signaling
Kai W. Wucherpfennig et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
T Cell Activation
Jennifer E. Smith-Garvin et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Inositol trisphosphate and calcium signalling mechanisms
Michael J. Berridge
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
Laura A. Johnson et al.
BLOOD (2009)
Nck adapter proteins: functional versatility in T cells
Marcus Lettau et al.
CELL COMMUNICATION AND SIGNALING (2009)
Crk and CrkL adaptor proteins: networks for physiological and pathological signaling
Raymond B. Birge et al.
CELL COMMUNICATION AND SIGNALING (2009)
The XLP syndrome protein SAP interacts with SH3 proteins to regulate T cell signaling and proliferation
Chengjun Li et al.
CELLULAR SIGNALLING (2009)
Dendritic Cell Vaccination Combined with CTLA4 Blockade in Patients with Metastatic Melanoma
Antoni Ribas et al.
CLINICAL CANCER RESEARCH (2009)
Regulation of the immune response by stress-activated protein kinases
Mercedes Rincon et al.
IMMUNOLOGICAL REVIEWS (2009)
T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
Robert J. Salmond et al.
IMMUNOLOGICAL REVIEWS (2009)
CARMA1-mediated NF-kappa B and JNK activation in lymphocytes
Marzenna Blonska et al.
IMMUNOLOGICAL REVIEWS (2009)
Importance and mechanism of 'switch' function of SAP family adapters
Andre Veillette et al.
IMMUNOLOGICAL REVIEWS (2009)
SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels
Ulrike Lorenz
IMMUNOLOGICAL REVIEWS (2009)
Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk
Julie A. Readinger et al.
IMMUNOLOGICAL REVIEWS (2009)
Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia
Karel Svojgr et al.
IMMUNOLOGY LETTERS (2009)
The αβ T Cell Receptor Is an Anisotropic Mechanosensor
Sun Taek Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Cytoplasmic Tail of the T Cell Receptor CD3 ε Subunit Contains a Phospholipid-Binding Motif that Regulates T Cell Functions
Laura M. DeFord-Watts et al.
JOURNAL OF IMMUNOLOGY (2009)
The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-κB and activate T cells
Sung-Gyoo Park et al.
NATURE IMMUNOLOGY (2009)
The Safety on the TCR Trigger
Michael S. Kuhns et al.
CELL (2008)
Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ε Cytoplasmic Tyrosine-Based Motif
Chenqi Xu et al.
CELL (2008)
Calcium signaling in lymphocytes
Masatsup Oh-Hora et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
Diacylglycerol kinases in immune cell function and self-tolerance
Xiao-Ping Zhong et al.
IMMUNOLOGICAL REVIEWS (2008)
Spatiotemporal regulation of ERK2 by dual specificity phosphatases
Christopher J. Caunt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers
Aubin Penna et al.
NATURE (2008)
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
Linda V. Sinclair et al.
NATURE IMMUNOLOGY (2008)
Synergistic control of T cell development and tumor suppression by diacylglycerol kinase α and ζ
Rishu Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation
Maria I. Lioudyno et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
F. Stephen Hodi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
CTLA-4 blockade increases IFNγ-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
Chrysoula I. Liakou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The role of Ras signaling in lupus T lymphocytes: Biology and pathogenesis
Adam Mor et al.
CLINICAL IMMUNOLOGY (2007)
The differential regulation of lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses
Louise McNeill et al.
IMMUNITY (2007)
Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties
Bruno Laugel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Calcium-dependent transcription of cytokine genes in T lymphocytes
Magali Savignac et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist
Morgan Huse et al.
IMMUNITY (2007)
The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance
Yun-Cai Liu
SEMINARS IN IMMUNOLOGY (2007)
SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptorinduced association between SLP-76 and ITK
Yaron Bogin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Dual role of SLP-76 in mediating T cell receptor-induced activation of phospholipase C-γ1
Dvora Beach et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptor-signaling pathway
Marzenna Blonska et al.
IMMUNITY (2007)
Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits
Alexander B. Sigalov et al.
BIOCHEMISTRY (2006)
T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-α
Yuanyuan Zha et al.
NATURE IMMUNOLOGY (2006)
Antigen-receptor signaling to nuclear factor κB
Jan Schulze-Luehrmann et al.
IMMUNITY (2006)
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy
Benjamin A. Olenchock et al.
NATURE IMMUNOLOGY (2006)
SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms
Takashi Nagaishi et al.
IMMUNITY (2006)
NF-κB and the immune response
M. S. Hayden et al.
ONCOGENE (2006)
Transcriptional regulation via the NF-κB signaling module
A. Hoffmann et al.
ONCOGENE (2006)
Cancer regression in patients after transfer of genetically engineered lymphocytes
Richard A. Morgan et al.
SCIENCE (2006)
The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation
Cuiping Gu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells
Luana O Atherly et al.
IMMUNITY (2006)
Regulation of naive T cell function by the NF-κB2 pathway
Naozumi Ishimaru et al.
NATURE IMMUNOLOGY (2006)
CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry
M. Vig et al.
SCIENCE (2006)
Deciphering the pathway from the TCR to NF-κB
R Weil et al.
CELL DEATH AND DIFFERENTIATION (2006)
Identification of substrates of human protein-tyrosine phosphatase PTPN22
JS Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
CARMA1 is required for Akt-mediated NF-κB activation in T cells
P Narayan et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The TCR C beta FG loop regulates alpha beta T cell development
Maki Touma et al.
JOURNAL OF IMMUNOLOGY (2006)
SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond
GA Koretzky et al.
NATURE REVIEWS IMMUNOLOGY (2006)
Phosphorylation of CARMA1 plays a critical role in T cell receptor-mediated NF-κB activation
R Matsumoto et al.
IMMUNITY (2005)
The p38 mitogen-activated protein kinase regulates effector functions of primary human CD4 T cells
F Dodeller et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2005)
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
W Kolch
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane
SYL Zhang et al.
NATURE (2005)
Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse
PP Yachi et al.
NATURE IMMUNOLOGY (2005)
NFAT proteins: Key regulators of T-cell development and function
F Macian
NATURE REVIEWS IMMUNOLOGY (2005)
Mutation of the phospholipase C-γ1-binding site of LAT affects both positive and negative thymocyte selection
CL Sommers et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases
JM Salvador et al.
NATURE IMMUNOLOGY (2005)
CD8αα-mediated survival and differentiation of CD8 memory T cell precursors
LT Madakamutil et al.
SCIENCE (2004)
Positive and negative adaptors in T-cell signalling
B Wilkinson et al.
IMMUNOLOGY (2004)
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
V Heissmeyer et al.
NATURE IMMUNOLOGY (2004)
Bcl10 activates the NF-κB pathway through ubiquitination of NEMO
HL Zhou et al.
NATURE (2004)
Central memory and effector memory T cell subsets: Function, generation, and maintenance
F Sallusto et al.
ANNUAL REVIEW OF IMMUNOLOGY (2004)
Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation
EH Palacios et al.
ONCOGENE (2004)
ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation
HY Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase itch
M Gao et al.
SCIENCE (2004)
Diacylglycerol-dependent binding recruits PKCθ and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes
S Carrasco et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
LAT: a T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways
CL Sommers et al.
BIOESSAYS (2004)
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
N Sakaguchi et al.
NATURE (2003)
A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8
PW Kim et al.
SCIENCE (2003)
Enhanced T cell responses due to diacylglycerol kinase ξ deficiency
XP Zhong et al.
NATURE IMMUNOLOGY (2003)
SLAM-associated protein deficiency causes imbalanced early signal transduction and blocks downstream activation in T cells from X-linked lymphoproliferative disease patients
S Sanzone et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site
R Zeng et al.
JOURNAL OF IMMUNOLOGY (2003)
Negative regulation of T cell antigen receptor-mediated Crk-L-C3G signaling and cell adhesion by Cbl-b
WY Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mechanism of Lck recruitment to the T-cell receptor cluster as studied by single-molecule-fluorescence video Imaging
H Ike et al.
CHEMPHYSCHEM (2003)
Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor ζ chain by the protein tyrosine kinase Lck
HR Housden et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates
HY Wang et al.
NATURE IMMUNOLOGY (2003)
Negative regulation of Rap1 activation by the Cbl E3 ubiquitin ligase
Y Shao et al.
EMBO REPORTS (2003)
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
I Stefanová et al.
NATURE IMMUNOLOGY (2003)
Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor
D Davidson et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15
RJ Brentjens et al.
NATURE MEDICINE (2003)
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation
S Latour et al.
NATURE CELL BIOLOGY (2003)
Involvement of Crk adapter proteins in regulation of lymphoid cell functions
S Gelkop et al.
IMMUNOLOGIC RESEARCH (2003)
c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation
M Naramura et al.
NATURE IMMUNOLOGY (2002)
SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation
LT Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Direct observation of ligand recognition by T cells
DJ Irvine et al.
NATURE (2002)
The Nck family of adapter proteins:: Regulators of actin cytoskeleton
L Buday et al.
CELLULAR SIGNALLING (2002)
Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase ζ
XP Zhong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Essential role of NF-κB-inducing kinase in T cell activation through the TCR/CD3 pathway
M Matsumoto et al.
JOURNAL OF IMMUNOLOGY (2002)
VAV proteins as signal integrators for multi-subunit immune-recognition receptors
M Turner et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Transcriptional mechanisms underlying lymphocyte tolerance
F Macián et al.
CELL (2002)
C-jun NH2-terminal kinase (JNK)1 and JNK2 have distinct roles in CD8+ T cell activation
D Conze et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Differential role of SLP-76 domains in T cell development and function
L Kumar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells
M Guirado et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Crk family adaptors - signalling complex formation and biological roles
SM Feller
ONCOGENE (2001)
Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap
EK Griffiths et al.
SCIENCE (2001)
Coupling of the TCR to integrin activation by SLAP-130/Fyb
EJ Peterson et al.
SCIENCE (2001)
Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule
JH Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Identification of the minimal tyrosine residues required for linker for activation of T cell function
J Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cbl promotes ubiquitination of the T cell receptor ζ through an adaptor function of Zap-70
HY Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Identification of a phospholipase C-γ1 (PLC-γ1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-γ1 and NFAT
D Yablonski et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase
GG Chiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structure of a human γδ T-cell antigen receptor
TJ Allison et al.
NATURE (2001)
CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A
LM Shlapatska et al.
JOURNAL OF IMMUNOLOGY (2001)
Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter
O Kaminuma et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT)
C Hübener et al.
IMMUNOGENETICS (2001)
Signal transduction by MAP kinases in T lymphocytes
M Rincón et al.
ONCOGENE (2001)
Requirement for the SLP-76 adaptor CADS in T cell development
J Yoder et al.
SCIENCE (2001)
Dynamic actin polymerization drives T cell receptor-induced spreading: A role for the signal transduction adaptor LAT
SC Bunnell et al.
IMMUNITY (2001)
Mammalian MAP kinase signalling cascades
LF Chang et al.
NATURE (2001)
A deletion in the gene encoding the CD45 antigen in a patient with SCID
EZ Tchilian et al.
JOURNAL OF IMMUNOLOGY (2001)
Severe combined immunodeficiencies (SCID)
A Fischer
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2000)
Signal transduction by the JNK group of MAP kinases
RJ Davis
CELL (2000)
Signaling takes shape in the immune system
ML Dustin et al.
CELL (2000)
CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling
JR Dorfman et al.
NATURE IMMUNOLOGY (2000)
RasGRP essential for mouse thymocyte differentiation and TCR signaling
NA Dower et al.
NATURE IMMUNOLOGY (2000)
Transmembrane phosphoprotein Cbp positively regulates the activity of the carboxyl-terminal Src kinase, Csk
S Takeuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Serine 6 of Lck tyrosine kinase: A critical site for Lck myristoylation, membrane localization, and function in T lymphocytes
K Yasuda et al.
JOURNAL OF IMMUNOLOGY (2000)
A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation
KG Johnson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface
C Wülfing et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Association of Grb2 Gads, and phospholipase C-γ1 with phosphorylated LAT tyrosine residues -: Effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling
WG Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling
ML Dustin et al.
NATURE IMMUNOLOGY (2000)
Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription
SP Hehner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
M Kawabuchi et al.
NATURE (2000)
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase Csk and is involved in regulation of T cell activation
T Brdicka et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton
M Krause et al.
JOURNAL OF CELL BIOLOGY (2000)
Down-regulation of the T cell receptor CD3ζ chain in rheumatoid arthritis (RA) and its influence on T cell responsiveness
L Berg et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2000)
How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures
RD Mullins
CURRENT OPINION IN CELL BIOLOGY (2000)
Cutting edge:: A novel function for the SLAP-130/FYB adapter protein in β1 integrin signaling and T lymphocyte migration
AJ Hunter et al.
JOURNAL OF IMMUNOLOGY (2000)
Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade
SC Bunnell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Human CD8β, but not mouse CD8β, can be expressed in the absence of CD8α as a ββ homodimer
L Devine et al.
JOURNAL OF IMMUNOLOGY (2000)
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
K Bachmaier et al.
NATURE (2000)
Lck activity controls CD4/CD8 T cell lineage commitment
G Hernandez-Hoyos et al.
IMMUNITY (2000)
Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase
K Katagiri et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)