Related references
Note: Only part of the references are listed.Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies
Qibin Qi et al.
GUT (2022)
Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites
Xiang Zhang et al.
GUT (2021)
The Aryl Hydrocarbon Receptor in Energy Balance: The Road from Dioxin-Induced Wasting Syndrome to Combating Obesity with Ahr Ligands
Nathaniel G. Girer et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier
Jiaojiao Li et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Anil Kumar et al.
NATURE COMMUNICATIONS (2021)
Regulation of host physiology and immunity by microbial indole-3-aldehyde
Teresa Zelante et al.
CURRENT OPINION IN IMMUNOLOGY (2021)
Overview of the Antioxidant and Anti-Inflammatory Activities of Selected Plant Compounds and Their Metal Ions Complexes
Paulina Mucha et al.
MOLECULES (2021)
Impact of Bacterial Metabolites on Gut Barrier Function and Host Immunity: A Focus on Bacterial Metabolism and Its Relevance for Intestinal Inflammation
Naschla Gasaly et al.
FRONTIERS IN IMMUNOLOGY (2021)
Tryptophan Metabolism and Related Pathways in Psychoneuroimmunology: The Impact of Nutrition and Lifestyle
Johanna M. Gostner et al.
NEUROPSYCHOBIOLOGY (2020)
Two apples a day modulate human:microbiome co-metabolic processing of polyphenols, tyrosine and tryptophan
Maria M. Ulaszewska et al.
EUROPEAN JOURNAL OF NUTRITION (2020)
Indole Alleviates Diet-Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3
Linqiang Ma et al.
HEPATOLOGY (2020)
Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine
Di Meng et al.
PEDIATRIC RESEARCH (2020)
Biphasic chemotaxis of Escherichia coli to the microbiota metabolite indole
Jingyun Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Differential activation of human pregnane X receptor PXR by isomeric mono-methylated indoles in intestinal and hepatic in vitro models
Barbora Vyhlidalova et al.
TOXICOLOGY LETTERS (2020)
Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists
Jiaxuan Chen et al.
SCIENCE ADVANCES (2020)
Medicinal Perspective of Indole Derivatives: Recent Developments and Structure-Activity Relationship Studies
Devendra Kumar et al.
CURRENT DRUG TARGETS (2020)
Targeting the pregnane X receptor using microbial metabolite mimicry
Zdenek Dvorak et al.
EMBO MOLECULAR MEDICINE (2020)
Dietary AhR Ligands Regulate AhRR Expression in Intestinal Immune Cells and Intestinal Microbiota Composition
Oliver Schanz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization
Barbora Vyhlidalova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Gut Microbial Metabolites of Aromatic Amino Acids as Signals in Host-Microbe Interplay
Yali Liu et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2020)
Indoxyl Sulfate, a Uremic Endotheliotoxin
Guillaume Lano et al.
TOXINS (2020)
Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile
Maria Arnoriaga-Rodriguez et al.
MICROBIOME (2020)
Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein
Hui-wen Xiao et al.
MICROBIOME (2020)
The aryl hydrocarbon receptor as a target of environmental stressors - Implications for pollution mediated stress and inflammatory responses
Christoph F. A. Vogel et al.
REDOX BIOLOGY (2020)
Roles of Hepatic Innate and Innate-Like Lymphocytes in Nonalcoholic Steatohepatitis
Yongyan Chen et al.
FRONTIERS IN IMMUNOLOGY (2020)
Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity
Fangcong Dong et al.
GUT MICROBES (2020)
Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor
Samantha A. Scott et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Endogenous Indole Pyruvate Pathway for Tryptophan Metabolism Mediated by IL4I1
Xia Zhang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)
Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging
Domonica N. Powell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity
Wenjing Yang et al.
NATURE COMMUNICATIONS (2020)
Indolepropionic Acid, a Metabolite of the Microbiome, Has Cytostatic Properties in Breast Cancer by Activating AHR and PXR Receptors and Inducing Oxidative Stress
Zsanett Sari et al.
CANCERS (2020)
Targeting the gut microbial metabolic pathway with small molecules decreases uremic toxin production
Yingyi Wang et al.
GUT MICROBES (2020)
Lemon Exosome-like Nanoparticles-Manipulated Probiotics Protect Mice from C. diff Infection
Chao Lei et al.
ISCIENCE (2020)
Paeoniflorin modulates gut microbial production of indole-3-lactate and epithelial autophagy to alleviate colitis in mice
Qilin Fan et al.
PHYTOMEDICINE (2020)
Indole-3-acetic acid synthesized through the indole-3-pyruvate pathway promotes Candida tropicalis biofilm formation
Masaru Miyagi et al.
PLOS ONE (2020)
Bacterially Derived Tryptamine Increases Mucus Release by Activating a Host Receptor in a Mouse Model of Inflammatory Bowel Disease
Yogesh Bhattarai et al.
ISCIENCE (2020)
Regulation of CAR and PXR Expression in Health and Disease
Martine Daujat-Chavanieu et al.
CELLS (2020)
Indole microbial intestinal metabolites expand the repertoire of ligands and agonists of the human pregnane X receptor
Peter Illes et al.
TOXICOLOGY LETTERS (2020)
Cellular Stress Upregulates Indole Signaling Metabolites in Escherichia coli
Chung Sub Kim et al.
CELL CHEMICAL BIOLOGY (2020)
The role of IL-22 in intestinal health and disease
Mary E. Keir et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner
Philip B. Busbee et al.
JCI INSIGHT (2020)
Indoles: metabolites produced by intestinal bacteria capable of controlling liver disease manifestation
T. Hendrikx et al.
JOURNAL OF INTERNAL MEDICINE (2019)
Aryl hydrocarbon receptor agonist indigo protects against obesity-related insulin resistance through modulation of intestinal and metabolic tissue immunity
Yi-Hsuan Lin et al.
INTERNATIONAL JOURNAL OF OBESITY (2019)
The Distribution of Tryptophan-Dependent Indole-3-Acetic Acid Synthesis Pathways in Bacteria Unraveled by Large-Scale Genomic Analysis
Pengfan Zhang et al.
MOLECULES (2019)
Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide
Matthew T. Henke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs
Anthony T. Virtue et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Indole Signaling at the Host-Microbiota-Pathogen Interface
Aman Kumar et al.
MBIO (2019)
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
Archana Kumari et al.
BIOORGANIC CHEMISTRY (2019)
Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats
Ze-Hua Zhao et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2019)
Gut Microbiota and Metabolome Response of Decaisnea insignis Seed Oil on Metabolism Disorder Induced by Excess Alcohol Consumption
Xiaoxia Liu et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)
Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress
Yun Ji et al.
NUTRIENTS (2019)
Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice
Tim Hendrikx et al.
GUT (2019)
Indole Treatment Alleviates Intestinal Tissue Damage Induced by Chicken Coccidiosis Through Activation of the Aryl Hydrocarbon Receptor
Woo H. Kim et al.
FRONTIERS IN IMMUNOLOGY (2019)
Microbiota-derived tryptophan indoles increase after gastric bypass surgery and reduce intestinal permeability in vitro and in vivo
M. Jennis et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2018)
The microbial metabolite indole-3-propionic acid improves glucose metabolism in rats, but does not affect behaviour
Anders Abildgaard et al.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2018)
Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor
Erica E. Alexeev et al.
AMERICAN JOURNAL OF PATHOLOGY (2018)
Colonic indole, gut bacteria metabolite of tryptophan, increases portal blood pressure in rats
Tomasz Huc et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2018)
Catalytic asymmetric synthesis of indole derivatives as novel α-glucosidase inhibitors in vitro
Mohammad Shahidul Islam et al.
BIOORGANIC CHEMISTRY (2018)
Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22
Qihang Hou et al.
CELL DEATH AND DIFFERENTIATION (2018)
Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion
Yogesh Bhattarai et al.
CELL HOST & MICROBE (2018)
A catch-22: Interleukin-22 and cancer
Pedro Hernandez et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2018)
Novel indole and triazole based hybrid molecules exhibit potent anti-adipogenic and antidyslipidemic activity by activating Wnt3a/β-catenin pathway
Sujith Rajan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
The gut microbiota metabolite indole alleviates liver inflammation in mice
Martin Beaumont et al.
FASEB JOURNAL (2018)
Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer
Thomas N. Y. Kwong et al.
GASTROENTEROLOGY (2018)
Aryl hydrocarbon receptor and intestinal immunity
Bruno Lamas et al.
MUCOSAL IMMUNOLOGY (2018)
Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health
Ludivine Laurans et al.
NATURE MEDICINE (2018)
The gut-liver axis and the intersection with the microbiome
Anupriya Tripathi et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)
Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes
Liping Zhao et al.
SCIENCE (2018)
Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages
Smitha Krishnan et al.
CELL REPORTS (2018)
The Association of Gut Microbiota with Nonalcoholic Steatohepatitis in Thais
Abhasnee Sobhonslidsuk et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism
Jing Gao et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2018)
The Aryl Hydrocarbon Receptor and Tumor immunity
Ping Xue et al.
FRONTIERS IN IMMUNOLOGY (2018)
The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity
Amina Metidji et al.
IMMUNITY (2018)
Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development
Yong-Soo Lee et al.
CELL HOST & MICROBE (2018)
Indole-3-Pyruvic Acid, an Aryl Hydrocarbon Receptor Activator, Suppresses Experimental Colitis in Mice
Reiji Aoki et al.
JOURNAL OF IMMUNOLOGY (2018)
Biodegradation and Biotransformation of Indole: Advances and Perspectives
Qiao Ma et al.
FRONTIERS IN MICROBIOLOGY (2018)
Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases
Susanna Nikolaus et al.
GASTROENTEROLOGY (2017)
Role of innate and adaptive immunity in obesity-associated metabolic disease
Tracey McLaughlin et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites
Dylan Dodd et al.
NATURE (2017)
Salt-responsive gut commensal modulates TH17 axis and disease
Nicola Wilck et al.
NATURE (2017)
Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells
Luisa Cervantes-Barragan et al.
SCIENCE (2017)
Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG
Martin Kroyer Rasmussen et al.
TOXICOLOGY LETTERS (2017)
Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study
Vanessa D. de Mello et al.
SCIENTIFIC REPORTS (2017)
Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation
Marta Wlodarska et al.
CELL HOST & MICROBE (2017)
Skatole metabolites in urine as a biological marker of pigs with enhanced hepatic metabolism
C. Brunius et al.
ANIMAL (2016)
Tissue distribution of aryl hydrocarbon receptor in the intestine: Implication of putative roles in tumor suppression
Togo Ikuta et al.
EXPERIMENTAL CELL RESEARCH (2016)
CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
Bruno Lamas et al.
NATURE MEDICINE (2016)
Signals from the gut microbiota to distant organs in physiology and disease
Bjoern Schroeder et al.
NATURE MEDICINE (2016)
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion
Anne F. McGettrick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Indoxyl Sulfate-Review of Toxicity and Therapeutic Strategies
Sheldon C. Leong et al.
TOXINS (2016)
Effect of High Dietary Tryptophan on Intestinal Morphology and Tight Junction Protein of Weaned Pig
Myrlene Carine B. Tossou et al.
BIOMED RESEARCH INTERNATIONAL (2016)
A Rapid and Specific Method for the Detection of Indole in Complex Biological Samples
Charles Darkoh et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2015)
Indole: a signaling molecule or a mere metabolic byproduct that alters bacterial physiology at a high concentration?
Jisun Kim et al.
JOURNAL OF MICROBIOLOGY (2015)
Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms
Andreas Bitter et al.
ARCHIVES OF TOXICOLOGY (2015)
Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine
Brianna B. Williams et al.
CELL HOST & MICROBE (2014)
Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
Madhukumar Venkatesh et al.
IMMUNITY (2014)
Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells
Catalin Chimerel et al.
CELL REPORTS (2014)
Microbiome-Derived Tryptophan Metabolites and Their Aryl Hydrocarbon Receptor-Dependent Agonist and Antagonist Activities
Un-Ho Jin et al.
MOLECULAR PHARMACOLOGY (2014)
Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22
Teresa Zelante et al.
IMMUNITY (2013)
The roles of aryl hydrocarbon receptor in immune responses
Nam Trung Nguyen et al.
INTERNATIONAL IMMUNOLOGY (2013)
A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice
A. Marcobal et al.
ISME JOURNAL (2013)
The Biochemical Mechanism of Auxin Biosynthesis by an Arabidopsis YUCCA Flavin-containing Monooxygenase
Xinhua Dai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Serotonin signalling in the gut-functions, dysfunctions and therapeutic targets
Gary M. Mawe et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)
Indole production by the tryptophanase TnaA in Escherichia coli is determined by the amount of exogenous tryptophan
Gang Li et al.
MICROBIOLOGY-SGM (2013)
Commensal Bacteria-Dependent Indole Production Enhances Epithelial Barrier Function in the Colon
Yosuke Shimada et al.
PLOS ONE (2013)
Indoxyl 3-sulfate stimulates Th17 differentiation enhancing phosphorylation of c-Src and STAT3 to worsen experimental autoimmune encephalomyelitis
Sung-Jun Hwang et al.
TOXICOLOGY LETTERS (2013)
Obesity Is Mediated by Differential Aryl Hydrocarbon Receptor Signaling hi Mice Fed a Western Diet
Joanna S. Kerley-Hamilton et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2012)
Identification and functional characterization of indole-3-acetamide-mediated IAA biosynthesis in plant-associated Fusarium species
Elena Tsavkelova et al.
FUNGAL GENETICS AND BIOLOGY (2012)
Nutritional Influences on Skatole Formation and Skatole Metabolism in the Pig
Raffael Wesoly et al.
Animals (2012)
Indole Transport across Escherichia coli Membranes
S. Pinero-Fernandez et al.
JOURNAL OF BACTERIOLOGY (2011)
The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation
Tarun Bansal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Indole as an intercellular signal in microbial communities
Jin-Hyung Lee et al.
FEMS MICROBIOLOGY REVIEWS (2010)
Understanding the role of tryptophan and serotonin metabolism in gastrointestinal function
D. Keszthelyi et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Organization of the ipdC region regulates IAA levels in different Azospirillum brasilense strains:: molecular and functional analysis of ipdC in strain SM
Mandira Malhotra et al.
ENVIRONMENTAL MICROBIOLOGY (2008)
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARγ in promoting steatosis
Jie Zhou et al.
GASTROENTEROLOGY (2008)
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243
T Nishizawa et al.
JOURNAL OF BACTERIOLOGY (2005)
Linking dioxins to diabetes: Epidemiology and biologic plausibility
RBJ Remillard et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2002)
Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfate
E Banoglu et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2002)
Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate
E Banoglu et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2001)
Oxidation of indole by cytochrome P450 enzymes
EMJ Gillam et al.
BIOCHEMISTRY (2000)