Journal
INTERFACE FOCUS
Volume 12, Issue 1, Pages -Publisher
ROYAL SOC
DOI: 10.1098/rsfs.2021.0040
Keywords
4-ply functionalized non-woven face mask; SARS-CoV-2; LibDock; algorithm; herbal phytochemicals; personal protective equipment
Categories
Funding
- DIAT (DU) [DIAT/F/ADM(RCT)/PA/08-2020/P-93]
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The study found that the face mask had a bacterial filtration efficacy of over 99% against Staphylococcus aureus, and a computational analysis showed effective docking performance of herbal phytochemicals against harmful virus structures. Additionally, the face mask met regulatory standards for breathability with a breathing resistance of 30 Pa at a flow rate of 30 l h(-1), indicating high potential for real-world applications.
The worldwide outbreak of SARS-CoV-2 infection has necessitated mandatory use of face masks, personal protective equipment and intake of a healthy diet for immunity boosting. As per WHO's recommendation, continuous use of masks has been proven effective in decreasing the SARS-CoV-2 infection rate. The present study reports on the bacterial filtration efficacy (BFE) of a novel 4-ply functionalized non-woven face mask. We synthesized a polypropylene-based fabric with inner layers of melt-blown fine fibres coated with polylactic acid and immune-boosting herbal phytochemicals. Experimental studies on the synthesized face mask demonstrated a BFE of greater than 99% against Staphylococcus aureus (a bacterium species frequently found in mammalian respiratory tract). A thorough computational analysis using LibDock algorithm demonstrated an effective docking performance of herbal phytochemicals against harmful virus structures. More importantly, the face mask also showed sufficient and stable breathability as per regulatory standards. A breathing resistance of 30 Pa at an aerosol flow rate of 30 l h(-1) was reported under standard temperature and pressure conditions, indicating a high potential for real-world applications.
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