Journal
METHODS AND PROTOCOLS
Volume 4, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/mps4040076
Keywords
cancer; depression; anxiety; insomnia; yoga; tai chi; qigong; relaxation; mind-body; mindfulness
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This study aims to assess the effectiveness and acceptability of mind-body therapies in cancer patients with depression, anxiety, and insomnia. Randomized controlled studies will be conducted, and pairwise and network meta-analyses will be used to evaluate the effects. The results of this study will provide guidance for clinical decision-making in treating psychological disturbances in cancer patients.
Depression, anxiety, and insomnia are common in cancer patients. Mind-body therapies (MBTs) are promising forms of treatment for cancer patients living with depression, anxiety, and insomnia. The objective of this study is to assess the effectiveness and acceptability of MBTs in cancer patients living with depression, anxiety, or insomnia. EMBase, PubMed, Cinahl, PsychINFO, IndMED, CSI-NISCAIR, CNKI, Clinicaltrial.gov, ChiCTR, and CTRI will be searched until October 2020 for relevant studies. Randomized controlled studies in which MBTs were tested in a cancer population will be selected. The authors of the selected studies will be contacted to obtain individual participant data. The participants who reached a defined clinical threshold for depression, anxiety, or insomnia will be selected for the three sub-studies on depression, anxiety, and insomnia, respectively. Pairwise and network meta-analyses will be used to assess the changes in depression, anxiety, sleep quality, and completion rate. We will assess the effect of the treatment dose (number and frequency of interventions) on effectiveness. The results of this study will inform clinical decision-making for the treatment of psychological disturbances in cancer patients. If MBTs are found effective, they will potentially be recommended as treatments for cancer patients with psychological symptoms.
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