Journal
CURRENT RESEARCH IN TOXICOLOGY
Volume 2, Issue -, Pages 329-340Publisher
ELSEVIER
DOI: 10.1016/j.crtox.2021.09.001
Keywords
Snake venom; Toxicity; Toxins; Inflammation; Peptides; Pain; Nociception
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Venom peptides have shown potential therapeutic effects by modulating various targets, with research progress made in clinical development targeting different diseases. Understanding venomous animals, their venoms, and pharmacological effects contributes to a better grasp of their therapeutic prospects.
Venom peptides have been evolving complex therapeutic interventions that potently and selectively modulate a range of targets such as ion channels, receptors, and signaling pathways of physiological processes making it potential therapeutic. Several venom peptides were deduced in vivo for clinical development targeting pain management, diabetes, cardiovascular diseases, antimicrobial activity. Several contributions have been detailed for a clear perspective for a better understanding of venomous animals, their venom, and their pharmacological effects. Here we unravel and summarize the recent advances in wide venom peptides across varieties of species for their therapeutics prospects.
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