4.1 Review

Magnetic nanoparticles in biomedical applications: A review

Journal

APPLIED SURFACE SCIENCE ADVANCES
Volume 6, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.apsadv.2021.100163

Keywords

Magnetic nanoparticles; Chronic diseases; Immunoassays; Biomedical applications

Funding

  1. Sao Paulo Research Foundation -FAPESP [2014/23546-1, 2016/00991-5, 2018/22214-6]
  2. National Council for scientific and technological development -CNPq

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Magnetic nanoparticles have significant technological benefits in biomedical applications, particularly in cancer treatment and drug targeting. They possess unique surface chemistry, non-toxicity, biocompatibility, and inducible magnetic moment. Future research should focus on developing advanced and high-performance magnetic nanoparticles.
Biomedical applications with emphasis on the design of smart materials, specifically magnetic nanoparticles (MNPs) are considered to have technological benefits because they can be manipulated using magnetic fields. Magnetic NPs have been widely used in hyperthermia, target drug delivery system, imaging, and extraction of biomolecules, postulating them also as an important tool in cancer treatment. Morphological structures of magnetic materials have drawn tremendous attention from diverse scientific fields due to their unique surface chemistry, nontoxicity, biocompatibility, and particularly their inducible magnetic moment. This review features recent research accomplishments made in the biomedical field using magnetic nanoparticles. The first part gives a comprehensive overview of magnetic nanoparticles in the treatment of chronic diseases and drug targeting. The second part includes the role of magnetic nanoparticles in electrochemical, optical-based immunoassays. The review also outlines the current challenges and future research perspectives for fostering advanced and high-performance magnetic nanoparticles in technological applications.

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