Journal
LAB ON A CHIP
Volume 21, Issue 17, Pages 3289-3297Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1lc00473e
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Funding
- University of Massachusetts Lowell start-up funds
- U.S. Army Medical Research (Defense Health Agency) [W81XWH-18-C-0032]
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A rapid and easy-to-use six-layer paper-based microfluidic device was developed for colorimetric detection of tacrolimus in a small volume of blood, using the principles of competitive immunoassays and vertical flow microfluidics.
Tacrolimus is one of the most effective and prevalent drugs used to combat vascularized composite allotransplantation rejection. We have fabricated a rapid and easy-to-use six-layer paper based microfluidic device using the principles of competitive immunoassays and vertical flow microfluidics for colorimetric detection of tacrolimus in a small volume of blood.
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