Journal
SEMINARS IN IMMUNOLOGY
Volume 56, Issue -, Pages -Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.smim.2021.101536
Keywords
Atherosclerosis; Cardiovascular disease; Inflammation; Myocardial infarction; Nanoparticles; Theranostics
Categories
Funding
- British Heart Foundation (BHF) [PG/19/84/34771, PG/21/10541]
- Engineering and Physical Sciences Research Council (EPSRC) [EP/L014165/1]
- European Research Council [726318]
- Wellcome Trust [204820/Z/16/Z]
- University of Glasgow Scottish Funding Council
- Global Challenges Research Fund
- European Research Council (ERC) [726318] Funding Source: European Research Council (ERC)
- Wellcome Trust [204820/Z/16/Z] Funding Source: Wellcome Trust
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Theranostics is an emerging field in clinical and preclinical research that combines diagnostics and therapy to simultaneously diagnose and treat pathologies. Nanoparticles are extensively used in theranostics due to their potential for targeting specific organs and multifunctionality, with key applications in imaging and treatment of cardiovascular inflammation being discussed in this review.
Theranostics, literally derived from the combination of the words diagnostics and therapy, is an emerging field of clinical and preclinical research, where contrast agents, drugs and diagnostic techniques are combined to simultaneously diagnose and treat pathologies. Nanoparticles are extensively employed in theranostics due to their potential to target specific organs and their multifunctional capacity. In this review, we will discuss the current state of theranostic nanomedicine, providing key examples of its application in the imaging and treatment of cardiovascular inflammation.
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