Journal
ACS APPLIED BIO MATERIALS
Volume 4, Issue 12, Pages 8172-8191Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsabm.1c00998
Keywords
gold nanoparticles; gold nanostructures; nanozymes; drug delivery; biosensing; therapeutics
Funding
- Department of Science and Technology (DST), New Delhi [1496]
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Gold has emerged as a superior element due to its widespread applications in electronic and medical fields, with its desirable physical, chemical, optical, and enzyme-like properties efficiently exploited for various biomedical purposes. While gold nanostructures offer unique advantages for specific biomedical applications, limitations during their usage are highlighted, necessitating solutions to overcome these challenges.
Gold (Au) has emerged as a superior element, because of its widespread applications in electronic and medical fields. The desirable physical, chemical, optical, and inherent enzyme-like properties of Au are efficiently exploited for detection, diagnostic, and therapeutic purposes. Au offers a unique advantage of fabricating gold nanostructures (GNS) having exact physical, chemical, optical, and enzyme-like properties required for the specific biomedical application. In this Review, the emerging trend of GNS for various biomedical applications is highlighted. Some notable structural and chemical modifications achieved for the detection of biomolecules, pathogens, diagnosis of diseases, and therapeutic applications are discussed in brief. The limitations of GNS during biomedical usage are highlighted and the way forward to overcome these limitations are discussed.
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