Journal
CHEMICAL SENSES
Volume 46, Issue -, Pages -Publisher
OXFORD UNIV PRESS
DOI: 10.1093/chemse/bjab045
Keywords
aging; cognitive impairment; olfactory training; olfactory testing; presbyosmia
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Age-related olfactory dysfunction, or presbyosmia, is a common sensory impairment in aging adults, especially in individuals with comorbid conditions or exposure to various insults. Olfactory dysfunction may serve as an early sign of Alzheimer's and Parkinson's disease, impacting nutrition, safety, social relationships, and even mortality.
Age-related olfactory dysfunction, or presbyosmia, is a common sensory impairment in aging adults. People in this demographic group with comorbid conditions or exposure to viral, traumatic, or environmental insults remain at the greatest risk for impairment. Several methods for assessing olfaction exist, but they are only available in special settings and require consideration of age, sex, ancestry, and cognition. Perhaps most importantly, olfactory dysfunction has been suggested as an early sign of Alzheimer's and Parkinson's disease and therefore may serve as a tool in the diagnosis and prognosis of these neurodegenerative conditions. Outside of this context, olfactory loss also impacts nutrition, safety, and social relationships, and even predicts mortality itself. This review covers the detection and manifestations of olfactory decline in aging individuals and the myriad ways in which olfactory impairment is connected to their health and well-being.
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