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Dysregulation of epithelial Na+ absorption induced by inhibition of the kinases TORC1 and TORC2
Morag K. Mansley et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions
B. Yang et al.
CELL DEATH AND DIFFERENTIATION (2010)
Functional Characterization of a Partial Loss-of-Function Mutation of the Epithelial Sodium Channel (ENaC) Associated with Atypical Cystic Fibrosis
Regina Huber et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2010)
Importance of ENaC-Mediated Sodium Transport in Alveolar Fluid Clearance Using Genetically-Engineered Mice
Edith Hummler et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2010)
ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1
Carole Planes et al.
EMBO MOLECULAR MEDICINE (2010)
Calcium Activates Nedd4 E3 Ubiquitin Ligases by Releasing the C2 Domain-mediated Auto-inhibition
Jian Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cys Palmitoylation of the β Subunit Modulates Gating of the Epithelial Sodium Channel
Gunhild M. Mueller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Allosteric Inhibition of the Epithelial Na+ Channel through Peptide Binding at Peripheral Finger and Thumb Domains
Ossama B. Kashlan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Glucocorticoid-induced Leucine Zipper 1 Stimulates the Epithelial Sodium Channel by Regulating Serum- and Glucocorticoid-induced Kinase 1 Stability and Subcellular Localization
Rama Soundararajan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Serum and Glucocorticoid-induced Kinase (SGK) 1 and the Epithelial Sodium Channel Are Regulated by Multiple with No Lysine (WNK) Family Members
Charles J. Heise et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Airway Surface Liquid Volume Regulation Determines Different Airway Phenotypes in Liddle Compared with βENaC-overexpressing Mice
Marcus A. Mall et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
EGF and Its Related Growth Factors Mediate Sodium Transport in mpkCCDc14 Cells via ErbB2 (neu/HER-2) Receptor
Vladislav Levchenko et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na plus self inhibition
Robert Rauh et al.
JOURNAL OF PHYSIOLOGY-LONDON (2010)
Regulation of WNK1 Expression by miR-192 and Aldosterone
Emilie Elvira-Matelot et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
mTOR Complex-2 Activates ENaC by Phosphorylating SGK1
Ming Lu et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Pendrin Modulates ENaC Function by Changing Luminal HCO3-
Vladimir Pech et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Sodium and Potassium Balance Depends on αENaC Expression in Connecting Tubule
Birgitte Monster Christensen et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Endothelin-1 Inhibits the Epithelial Na+ Channel through βPix/14-3-3/Nedd4-2
Tengis S. Pavlov et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
The cells and peripheral representation of sodium taste in mice
Jayaram Chandrashekar et al.
NATURE (2010)
Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension
Juliette Hadchouel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The epithelial sodium channel (ENaC): Mediator of the aldosterone response in the vascular endothelium?
Kristina Kusche-Vihrog et al.
STEROIDS (2010)
Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel
Christopher J. Passero et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms
Hong-Long Ji et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations
Per Svenningsen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
The Contribution of Epithelial Sodium Channels to Alveolar Function in Health and Disease
Douglas C. Eaton et al.
ANNUAL REVIEW OF PHYSIOLOGY (2009)
Revealing a subclinical salt-losing phenotype in heterozygous carriers of the novel S562P mutation in the α subunit of the epithelial sodium channel
Felix G. Riepe et al.
CLINICAL ENDOCRINOLOGY (2009)
Mutations in the Amiloride-Sensitive Epithelial Sodium Channel in Patients With Cystic Fibrosis-Like Disease
Abul Kalam Azad et al.
HUMAN MUTATION (2009)
A Functional Variant of NEDD4L Is Associated With Hypertension, Antihypertensive Response, and Orthostatic Hypotension
Fang Luo et al.
HYPERTENSION (2009)
Functional Regulation of the Epithelial Na+ Channel by IκB Kinase-β Occurs via Phosphorylation of the Ubiquitin Ligase Nedd4-2
Robert S. Edinger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The δ-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation
Silke Haerteis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases
Thomas R. Kleyman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice
Michelle L. Gumz et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel
Per Svenningsen et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Physiological functions of the HECT family of ubiquitin ligases
Daniela Rotin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Functional ENaC Channels Expressed in Endothelial Cells: a New Candidate for Mediating Shear Force
Su Wang et al.
MICROCIRCULATION (2009)
AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated
Joana Almaca et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2009)
Epithelial sodium channel regulated by differential composition of a signaling complex
Rama Soundararajan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
K+ secretion in the rat kidney: Na+ channel-dependent and -independent mechanisms
Gustavo Frindt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)
Epithelial Na+ channel δ subunit mediates acid-induced ATP release in the human skin
Hisao Yamamura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Expression, transcription, and possible antagonistic interaction of the human Nedd4L gene variant -: Implications for essential hypertension
Naomi Araki et al.
HYPERTENSION (2008)
An obligatory heterodimer of 14-3-3β and 14-3-3ε is required for aldosterone regulation of the epithelial sodium channel
Xiubin Liang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Nedd4-2 induces endocytosis and degradation of proteolytically cleaved epithelial Na+ channels
Rajesh Kabra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ENaC beta and gamma genes as modifier genes in cystic fibrosis
Marion Viel et al.
JOURNAL OF CYSTIC FIBROSIS (2008)
Liddle's syndrome caused by a novel missense mutation (P617L) of the epithelial sodium channel β subunit
Ermanno Rossi et al.
JOURNAL OF HYPERTENSION (2008)
Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome
Marko Bertog et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Deubiquitylation Regulates Activation and Proteolytic Cleavage of ENaC
Dorothee Ruffieux-Daidie et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Mechanisms of ENaC regulation and clinical implications
Vivek Bhalla et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Epithelial Na+ channel activation and processing in mice lacking SGK1
Geza Fejes-Toth et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Postnatal requirement of the epithelial sodium channel for maintenance of epidermal barrier function
Roch-Philippe Charles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3
Sheerazed Boulkroun et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2
Peijun P. Shi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel
Marcelo D. Carattino et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel
Michael B. Butterworth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Alveolar edema fluid clearance and acute lung injury
Yves Berthiaume et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2007)
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
Il-Ha Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Involvement of αENaC and Nedd4-2 in the conversion from lung fluid secretion to fluid absorption at birth in the rat as assayed by RNA interference analysis
Tianbo Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Reduced ENaC protein abundance contributes to the lower blood pressure observed in pendrin-null mice
Young Hee Kim et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Jayasankar Jasti et al.
NATURE (2007)
The role of α-, β-, and γ-ENaC subunits in distal lung epithelial fluid absorption induced by pulmonary edema fluid
Nael Elias et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site
Rebecca A. Falin et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
The PY motif of ENaC, mutated in Liddle syndrome, regulates channel internalization, sorting and mobilization from subapical pool
Chen Lu et al.
TRAFFIC (2007)
Autoinhibition of the HECT-Type ubiquitin ligase smurf2 through its c2 domain
Silke Wiesner et al.
CELL (2007)
GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2
Angeles Sanchez-Perez et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Cloning and functional expression of a new epithelial sodium channel δ subunit isoform differentially expressed in neurons of the human and monkey telencephalon
Teresa Giraldez et al.
JOURNAL OF NEUROCHEMISTRY (2007)
β-Liddle mutation of the epithelial sodium channel increases alveolar fluid clearance and reduces the severity of hydrostatic pulmonary oedema in mice
Nadia Randrianarison et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC
Ruifeng Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Trafficking of ENaC subunits in response to acute insulin in mouse kidney
Swasti Tiwari et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Polymorphism in NEDD4L Is Associated with Increased Salt Sensitivity, Reduced Levels of P-renin and Increased Levels of Nt-proANP
Jonas Dahlberg et al.
PLOS ONE (2007)
Inhibition of airway Na+ transport by respiratory syncytial virus
Karl Kunzelmann et al.
JOURNAL OF VIROLOGY (2007)
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo
Aaron M. Ring et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis
Aaron M. Ring et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the γ-subunit
James B. Bruns et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel α
Wenzheng Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
IGF-1 vs insulin: Respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line
E. Gonzalez-Rodriguez et al.
KIDNEY INTERNATIONAL (2007)
Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet
Dan Yang Huang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Dietary Cl- restriction upregulates pendrin expression within the apical plasma membrane of type B intercalated cells
Jill W. Verlander et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
SGK1 is not required for regulation of colonic ENaC activity
Rexhep Rexhepaj et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2006)
Regulation of maturation and processing of ENaC subunits in the rat kidney
Zuhal Ergonul et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
24-h ambulatory blood pressure is linked to chromosome 18q21-22 and genetic variation of NEDD4L associates with cross-sectional and longitudinal blood pressure in Swedes
C. Fava et al.
KIDNEY INTERNATIONAL (2006)
The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its α subunit
Marcelo D. Carattino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
14-3-3 isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels
Xiubin Liang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition
S Sheng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
14-3-3 mediates phosphorylation-dependent inhibition of the interaction between the ubiquitin E3 ligase Nedd4-2 and epithelial Na+ channels
Kazunori Nagaki et al.
BIOCHEMISTRY (2006)
Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats
J Song et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Dietary sodium intake regulates the ubiquitin-protein ligase nedd4-2 in the renal collecting system
Dominique Loffing-Cueni et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1
DY Huang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)
δ-subunit confers novel biophysical features to αβγ-human epithelial sodium channel (ENaC) via a physical interaction
HL Ji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Long-term effects of vasopressin on the subcellular localization of ENaC in the renal collecting system
D Sauter et al.
KIDNEY INTERNATIONAL (2006)
Structural determinants for high-affinity binding in a Nedd4 WW3*domain-Comm PY motif complex
V Kanelis et al.
STRUCTURE (2006)
Phosphatidylinositol 3,4,5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with γ-ENaC
MN Helms et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport
R Soundararajan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3
V Bhalla et al.
MOLECULAR ENDOCRINOLOGY (2005)
Mutations in the beta-subunit of the epithelial Na+ channel in patients with a cystic fibrosis-like syndrome
MB Sheridan et al.
HUMAN MOLECULAR GENETICS (2005)
Acute regulation of epithelial sodium channel by anionic phospholipids
HP Ma et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Association of NEDD4L ubiquitin ligase with essential hypertension
CJ Russo et al.
HYPERTENSION (2005)
WNK1 activates SGK1 to regulate the epithelial sodium channel
BE Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells
MD Carattino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase
T Ichimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line
HP Gaeggeler et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Impaired regulation of renal K+ elimination in the sgk1-knockout mouse
DY Huang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)
Na channels in the rat connecting tubule
G Frindt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Protons activate the δ-subunit of the epithelial Na+ channel in humans
H Yamamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Identification of Murr1 as a regulator of the human δ epithelial sodium channel
W Biasio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A naturally occurring human Nedd4-2 variant displays impaired ENaC regulation in Xenopus laevis oocytes
F Fouladkou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport
A Náray-Fejes-Tóth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Influenza virus inhibits ENaC and lung fluid clearance
XJ Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na+ channel through convergent phosphorylation of Nedd4-2
PM Snyder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Direct activation of the epithelial Na+ channel by phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate produced by phosphoinositide 3-OH kinase
QS Tong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
M Mall et al.
NATURE MEDICINE (2004)
Maturation of the epithelial Na+ channel involves proteolytic processing of the α- and γ-subunits
RP Hughey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney -: Role of pendrin in mineralocorticoid-induced hypertension
JW Verlander et al.
HYPERTENSION (2003)
Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity
BL Blazer-Yost et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Mineralocorticoid effects in the kidney:: Correlation between αENaC, GILZ, and Sgk-1 mRNA expression and urinary excretion of Na+ and K+
OG Muller et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Effect of salt and water intake on epithelial sodium channel mRNA abundance in the kidney of salt-sensitive Sabra rats
C Nicco et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2003)
Functional interaction of CFTR and ENaC in sweat glands
MM Reddy et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2003)
Lung edema clearance:: 20 years of progress selected contribution:: Limiting Na+ transport rate in airway epithelia from α-ENaC transgenic mice:: a model for pulmonary edema
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JOURNAL OF APPLIED PHYSIOLOGY (2002)
Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na+ transport
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)
Epithelial sodium channel/degenerin family of ion channels: A variety of functions for a shared structure
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PHYSIOLOGICAL REVIEWS (2002)
Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT1 receptors
J Peti-Peterdi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
The ENaC channel is required for normal epidermal differentiation
T Mauro et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2002)
Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC)
HP Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Targeted proteomic profiling of renal Na+ transporter and channel abundances in angiotensin II type 1a receptor knockout mice
HL Brooks et al.
HYPERTENSION (2002)
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel
PM Snyder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+ transport
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)
Common variant of human NEDD4L activates a cryptic splice site to form a frameshifted transcript
DM Dunn et al.
JOURNAL OF HUMAN GENETICS (2002)
Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na+ channel cell surface expression
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EMBO JOURNAL (2001)
Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron
J Loffing et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2001)
Chronic exposure to vasopressin upregulates ENaC and sodium transport in the rat renal collecting duct and lung
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HYPERTENSION (2001)
The role of SGK1 in hormone-regulated sodium transport
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2001)
Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na+ channel regulation
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2001)
Solution structure of a Nedd4 WW domain-ENaC peptide complex
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NATURE STRUCTURAL BIOLOGY (2001)
Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system:: possible role of SGK
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2001)
The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel
KF Harvey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Transcriptome of a mouse kidney cortical collecting duct cell line: Effects of aldosterone and vasopressin
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Molecular mechanisms of human hypertension
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CELL (2001)
SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2001)
Clinical case seminar - Compound heterozygous mutations in the gamma subunit gene of ENaC (1627delG and 1570-1G -> A) in one sporadic Japanese patient with a systemic form of pseudohypoaldosteronism type 1
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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel
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FASEB JOURNAL (2001)
Acute differential regulation by corticosteroids of epithelial sodium channel subunit and Nedd4 mRNA levels in the distal colon
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PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2000)
Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2000)
Vasopressin-mediated regulation of epithelial sodium channel abundance in rat kidney
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2000)
Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb
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JOURNAL OF CELL BIOLOGY (2000)
Epithelial Na+ channel (ENaC) expression in the developing normal and abnormal human perinatal lung
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)
Regulation of sgk by aldosterone and its effects on the epithelial Na+ channel
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2000)
Acetylation: a regulatory modification to rival phosphorylation?
T Kouzarides
EMBO JOURNAL (2000)
Early aldosterone effect in distal colon by transcriptional regulation of ENaC subunits
HJ Epple et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2000)
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