3.8 Proceedings Paper

A COMPREHENSIVE REVIEW OF THREE-DIMENSIONAL NEURO-ORGANOIDS AND ENGINEERING BRAIN-ON-A-CHIP MICROFLUIDIC DEVICES

Publisher

AMER SOC MECHANICAL ENGINEERS

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Funding

  1. Burroughs Wellcome Fund Physician Scientist Award

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This review focuses on advances in three-dimensional organoids, with a particular emphasis on the engineering of microfluidic device platforms for investigating neuro-organoids. The paper also assesses current limitations in microfluidic design to realize the full potential of brain-on-a-chip devices.
The focus of this review is to describe advances in three-dimensional (3D) organoids reported in the literature with an emphasis on the engineering of microfluidic device platforms for investigating neuro-organoids. Furthermore, the paper will assess current limitations in microfluidic design that must be addressed for realizing the full potential of brain-on-a-chip devices.

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