4.7 Article

Nanobodies: an unexplored opportunity to combat COVID-19

Journal

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
Volume 40, Issue 7, Pages 3129-3131

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/07391102.2020.1845801

Keywords

Camelid; heavy-chain antibody; SARS-CoV-2; therapeutic; diagnostic

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COVID-19 is a highly contagious disease caused by SARS-CoV-2, with rapid global spread and high fatality rates. Currently, there are no available vaccines or specific therapies. This paper highlights the potential utility of nanobodies for therapeutic and diagnostic interventions.
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). This virus is capable of human-to-human transmission, and is spreading rapidly round the globe, with markedly high fatality rates. Unfortunately, there are neither vaccines nor specific therapies available to combat it, and the developments of such approaches depend on pursuing multiple avenues in biomedical science. Accordingly, in this paper we highlight one such avenue-nanobodies-for potential utility in therapeutic and diagnostic interventions to combat COVID-19. Communicated by Ramaswamy H. Sarma

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