4.4 Article

Evaluation of Serum Creatinine Changes With Integrase Inhibitor Use in Human Immunodeficiency Virus-1 Infected Adults

Journal

OPEN FORUM INFECTIOUS DISEASES
Volume 3, Issue 2, Pages -

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofw053

Keywords

creatinine clearance; human immunodeficiency virus; integrase inhibitor; renal

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This retrospective chart review evaluated changes in serum creatinine and creatinine clearance (CrCl) after initiation of an integrase inhibitor (INSTI)-based regimen as initial treatment in human immunodeficiency virus-infected adults. Serum creatinine and CrCl changes were similar to those seen in clinical trials for INSTIs. No renal-related serious adverse events or discontinuations occurred.

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