4.5 Article

Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School

Journal

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
Volume 52, Issue 1, Pages 392-401

Publisher

SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10803-021-04949-2

Keywords

Autism spectrum disorder; Trajectories; Chronogeneity; Turning points

Funding

  1. Canadian Institutes of Health Research
  2. Autism Speaks
  3. Government of British Columbia
  4. Alberta Innovates Health Solutions
  5. Kids Brain Health Network
  6. Sinneave Family Foundation
  7. Hamilton Health Sciences Early Career Award
  8. Joan & Jack Craig Chair in Autism Research
  9. Tier 1 Canada Research Chair in Economic Evaluation and Technology Assessment in Child Health
  10. Stollery Children's Hospital Foundation Chair in Autism
  11. Patsy and Jamie Anderson Chair in Child and Youth Mental Health

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This study examined trajectories of autistic symptom severity in 187 children with ASD, identifying two main trajectory types and a turning point at age 6 during the transition to school. The results can inform the development of more personalized services for children with ASD transitioning into the school system.
This study examined the trajectories of autistic symptom severity in an inception cohort of 187 children with ASD assessed across four time points from diagnosis to age 10. Trajectory groups were derived using multivariate cluster analysis. A two trajectory/cluster solution was selected. Change in trajectory slopes revealed a turning point marked by plateauing in symptom reduction during the period of transition to school (age 6) for one of the two trajectories. Trajectories were labelled: Continuously Improving (27%) and Improving then Plateauing (73% of sample). Children in the two trajectories differed in levels of symptom severity, language, cognitive, and adaptive functioning skills. Study findings can inform the development of more personalized services for children with ASD transitioning into the school system.

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