Journal
OPEN FORUM INFECTIOUS DISEASES
Volume 3, Issue 1, Pages -Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofw023
Keywords
critically ill; influenza diagnosis; lower respiratory tract; upper respiratory tract
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Funding
- National Institute of Allergy and Infectious Diseases of the National Institutes of Health [T32 AI007433]
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Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza testing of both URT and LRT specimens to improve diagnostic yield and possibly inform prognosis.
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