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The active surveillance management approach for patients with low risk papillary thyroid microcarcinomas: is China ready?

Journal

CANCER BIOLOGY & MEDICINE
Volume 19, Issue 5, Pages 619-634

Publisher

CHINA ANTI-CANCER ASSOC
DOI: 10.20892/j.issn.2095-3941.2021.0058

Keywords

Papillary thyroid carcinoma; microcarcinoma; active surveillance; observation

Funding

  1. National Natural Science Foundation of China [81760142]
  2. Construction Project of Clinical Research Centre of General Surgical Disease in Yunnan Province [2X2019-03-03]
  3. Ten Thousand People Plan of Yunnan Province-Medical Experts Project [RLCRC20210412]

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Low risk papillary thyroid microcarcinoma (PTMC) has become a clinical and social issue due to exponential increases in incidences, leading to the increasing popularity of an active surveillance (AS) approach worldwide. However, Chinese thyroid surgeons lag behind in knowledge of AS practices, and a management approach based on the Chinese population should be developed to reduce disease progression risk. It is important for surgeons to understand patient willingness, impact on the medical billing system, and doctor enthusiasm for AS implementation in China.
Due to exponential increases in incidences, low risk papillary thyroid microcarcinoma (PTMC) has become a clinical and social issue in recent years. An active surveillance (AS) management approach is an alternative to immediate surgery for patients with low risk PTMC. With decreased doubts about the safety and validity due to evidence from a large number of studies, the AS approach has become increasingly popular worldwide. However, Chinese thyroid surgeons still lag behind other countries in their knowledge of clinical practices and research related to AS. To promote the implementation of AS in China, thyroid surgeons should understand the implications, advantages, and disadvantages of management approaches for AS, and should also consider the willingness of Chinese patients, the impact on the medical billing system, and the enthusiasm of doctors. Thus, a management approach for AS based on the Chinese population should be developed to reduce the risk of disease progression and enhance patient adherence. Herein, we summarize the recent research achievements and deficiencies in AS approaches, and describe the initial experiences regarding AS in the Chinese population, in order to assist Chinese thyroid surgeons in preparing for AS management in the era of PTMC precision medicine.

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