4.2 Article

Genome-wide association studies for growth traits in broilers

Journal

BMC GENOMIC DATA
Volume 23, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s12863-021-01017-7

Keywords

Broiler; Growth trait; Body weight; GWAS; Heritability

Funding

  1. National Natural Science Foundation of China [31972549]
  2. China Agriculture Research System of MOF [CARS-41]
  3. China Agriculture Research System of MARA [CARS-41]
  4. Heilongjiang Postdoctoral Financial Assistance [LBH-Q20006]
  5. Academic BackboneProject of Northeast Agricultural University [17XG18]

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This study estimated the genetic parameters of growth traits in broilers and identified several candidate genes associated with rapid growth, providing important information about the genetic foundation of growth traits in broilers.
Background The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers. Results In the current study, we estimated the genetic parameters of eight growth traits in broilers and carried out the genome-wide association studies for these growth traits. A total of 113 QTNs discovered by multiple methods together, and some genes, including ACTA1, IGF2BP1, TAPT1, LDB2, PRKCA, TGFBR2, GLI3, SLC16A7, INHBA, BAMBI, APCDD1, GPR39, and GATA4, were identified as important candidate genes for rapid growth in broilers. Conclusions The results of this study will provide important information for understanding the genetic foundation of growth traits in broilers.

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