4.6 Review

Military traumatic brain injury: a challenge straddling neurology and psychiatry

Journal

MILITARY MEDICAL RESEARCH
Volume 9, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s40779-021-00363-y

Keywords

Shellshock; Military; Traumatic brain injury; Diagnosis; Treatment; Comorbidity

Funding

  1. Zhejiang Provincial Key Research and Development Program [2021C03107]

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Military psychiatry, a new subcategory of psychiatry, is playing an important role in war. This review examines military research, summarizes epidemiological data, neuropathology, and research achievements in diagnosis and treatment technology, and discusses the comorbidity and sequelae of military traumatic brain injury (TBI). Advances in neuroimaging and molecular biology have greatly enhanced the understanding of TBI, revealing abnormal protein accumulation and brain metabolism abnormalities involved in its development. TBI, based on organic injury, is distinct from other mental disorders and presents a new challenge at the intersection of neurology and psychiatry.
Military psychiatry, a new subcategory of psychiatry, has become an invaluable, intangible effect of the war. In this review, we begin by examining related military research, summarizing the related epidemiological data, neuropathology, and the research achievements of diagnosis and treatment technology, and discussing its comorbidity and sequelae. To date, advances in neuroimaging and molecular biology have greatly boosted the studies on military traumatic brain injury (TBI). In particular, in terms of pathophysiological mechanisms, several preclinical studies have identified abnormal protein accumulation, blood-brain barrier damage, and brain metabolism abnormalities involved in the development of TBI. As an important concept in the field of psychiatry, TBI is based on organic injury, which is largely different from many other mental disorders. Therefore, military TBI is both neuropathic and psychopathic, and is an emerging challenge at the intersection of neurology and psychiatry.

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