4.6 Article

Hypoxia-Activated Albumin-Binding Exatecan Prodrug for Cancer Therapy

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Reversible Dimerization of Human Serum Albumin

Alexey Chubarov et al.

Summary: The Pulsed Dipolar Spectroscopy (PDS) methods of Electron Paramagnetic Resonance (EPR) were used to study reversible non-covalent dimers of Human Serum Albumin (HSA), showing that chemical modifications of Cys-34 can affect dimerization. The weak non-covalent dimers formed by HSA at physiological concentrations have a well-defined structure and can easily revert back to monomers, playing an important role in transport and binding processes.

MOLECULES (2021)

Review Biotechnology & Applied Microbiology

Spotlight on aldoxorubicin (INNO-206) and its potential in the treatment of soft tissue sarcomas: evidence to date

Lee D. Cranmer

ONCOTARGETS AND THERAPY (2019)

Review Chemistry, Multidisciplinary

The Role of Organic Synthesis in the Emergence and Development of Antibody-Drug Conjugates as Targeted Cancer Therapies

K. C. Nicolaou et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Medicinal

Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates

Wei Li et al.

ACS MEDICINAL CHEMISTRY LETTERS (2019)

Review Gastroenterology & Hepatology

New Insights About Albumin and Liver Disease

Joana R. Carvalho et al.

ANNALS OF HEPATOLOGY (2018)

Article Pharmacology & Pharmacy

Bioresponsive albumin-conjugated paclitaxel prodrugs for cancer therapy

Jincheng Yang et al.

DRUG DELIVERY (2018)

Review Pharmacology & Pharmacy

Applications of stimuli-responsive nanoscale drug delivery systems in translational research

Mengjie Gu et al.

DRUG DISCOVERY TODAY (2018)

Review Materials Science, Biomaterials

Albumin based versatile multifunctional nanocarriers for cancer therapy: Fabrication, surface modification, multimodal therapeutics and imaging approaches

Ritu R. Kudarha et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Article Oncology

Molecular Pathways: Hypoxia-Activated Prodrugs in Cancer Therapy

Natalia Baran et al.

CLINICAL CANCER RESEARCH (2017)

Review Biochemistry & Molecular Biology

The Warburg Effect: How Does it Benefit Cancer Cells?

Maria V. Liberti et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Article Biochemical Research Methods

Cys34-PEGylated Human Serum Albumin for Drug Binding and Delivery

Jonathan G. Mehtala et al.

BIOCONJUGATE CHEMISTRY (2015)

Review Pharmacology & Pharmacy

Classification of stimuli-responsive polymers as anticancer drug delivery systems

Bita Taghizadeh et al.

DRUG DELIVERY (2015)

Article Chemistry, Medicinal

Synthesis and Antitumor Efficacy of a β-Glucuronidase-Responsive Albumin-Binding Prodrug of Doxorubicin

Thibaut Legigan et al.

JOURNAL OF MEDICINAL CHEMISTRY (2012)

Review Chemistry, Multidisciplinary

Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

Felix Kratz

JOURNAL OF CONTROLLED RELEASE (2008)

Article Chemistry, Medicinal

Development of a novel albumin-binding prodrug that is cleaved by urokinase-type-plasminogen activator (uPA)

Da-Eun Chung et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)

Review Oncology

Exploiting tumour hypoxia in cancer treatment

JM Brown et al.

NATURE REVIEWS CANCER (2004)

Review Oncology

Hypoxia - A key regulatory factor in tumour growth

AL Harris

NATURE REVIEWS CANCER (2002)