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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
Introduction to NF-κB:: players, pathways, perspectives
T. D. Gilmore
ONCOGENE (2006)
Stereotactic body radiation therapy (SBRT) for lung metastases
Paul Okunieff et al.
ACTA ONCOLOGICA (2006)
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
Xing Fan et al.
CANCER RESEARCH (2006)
A phase II trial of accelerated radiotherapy using weekly stereotactic conformal boost for supratentorial glioblastoma multiforme: RTOG 0023
Robert Cardinale et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Jeongwu Lee et al.
CANCER CELL (2006)
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
HS Phillips et al.
CANCER CELL (2006)
Notch signalling in vertebrate neural development
A Louvi et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Tp53-gene transfer induces hypersensitivity to low doses of X-rays in glioblastoma cells: a strategy to convert a radio-resistant phenotype into a radiosensitive one
P D'Avenia et al.
CANCER LETTERS (2006)
Biologic basis for combining drugs with radiation
GD Wilson et al.
SEMINARS IN RADIATION ONCOLOGY (2006)
Genetic alteration and expression of the phosphoinositol-3-kinase/Akt pathway genes PIK3CA and PIKE in human glioblastomas
CB Knobbe et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2005)
Radiotherapeutic techniques for prostate cancer, dose escalation and brachytherapy
VS Khoo
CLINICAL ONCOLOGY (2005)
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
R Abounader et al.
NEURO-ONCOLOGY (2005)
The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant glioma
MN Tsao et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Cdk1-dependent regulation of the mitotic inhibitor Wee1
SL Harvey et al.
CELL (2005)
Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation
D Zencak et al.
JOURNAL OF NEUROSCIENCE (2005)
Targeting the c-Met pathway potentiates glioblastoma responses to γ-radiation
BC Lal et al.
CLINICAL CANCER RESEARCH (2005)
Aberrant stat3 signaling by interleukin-4 in malignant glioma cells:: Involvement of IL-13Rα2
SO Rahaman et al.
CANCER RESEARCH (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
The concept of synthetic lethality in the context of anticancer therapy
WG Kaelin
NATURE REVIEWS CANCER (2005)
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
C Leung et al.
NATURE (2004)
Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas
CB Knobbe et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2004)
The contribution of epidermal growth factor receptor (EGFR) signaling pathway to radioresistance in human gliomas: A review of preclinical and correlative clinical data
A Chakravarti et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)
Role of cell cycle in mediating sensitivity to radiotherapy
TM Pawlik et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)
Oxidative stress, redox, and the tumor microenvironment
JA Cook et al.
SEMINARS IN RADIATION ONCOLOGY (2004)
The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38γ-independent pathway
E Tosti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: Report of Radiation Therapy Oncology Group 93-05 protocol
L Souhami et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)
The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
A Chakravarti et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Technical aspects of daily online positioning of the prostate for three-dimensional conformal radiotherapy using an electronic portal imaging device
MG Herman et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2003)
Hypofractionated stereotactic radiotherapy alone without whole-brain irradiation for patients with solitary and oligo brain metastasis using noninvasive fixation of the skull
HI Aoyama et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2003)
Phase II study of high central dose gamma knife radiosurgery and marimastat in patients with recurrent malignant glioma
DA Larson et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2002)
Importance of hypoxia in the biology and treatment of brain tumors
JPS Knisely et al.
NEUROIMAGING CLINICS OF NORTH AMERICA (2002)
RhoB controls the 24 kDa FGF-2-induced radioresistance in HeLa cells by preventing post-mitotic cell death
I Ader et al.
ONCOGENE (2002)
Medulloblastoma growth inhibition by Hedgehog pathway blockade
DM Berman et al.
SCIENCE (2002)
Effects of NFκB decoy oligonucleotides released from biodegradable polymer microparticles on a glioblastoma cell line
JS Gill et al.
BIOMATERIALS (2002)
Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation
C Delmas et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
MRK, a mixed lineage kinase-related molecule that plays a role in γ-radiation-induced cell cycle arrest
EA Gross et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Constitutive activation of Stat3α in brain tumors:: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2)
LK Schaefer et al.
ONCOGENE (2002)
Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells
G Lammering et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)
Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization
G Lammering et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
Phase II, two-arm RTOG trial (94-11) of bischloroethyl-nitrosourea plus accelerated hyperfractionated radiotherapy (64.0 or 70.4 gy) based on tumor volume (> 20 or ≤ 20 CM2, respectively) in the treatment of newly-diagnosed radiosurgery-ineligible glioblastoma multiforme patients
C Coughlin et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2000)
Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells
W Roth et al.
ONCOGENE (2000)
Single-arm, open-label phase II study of intravenously administered tirapazamine and radiation therapy for glioblastoma multiforme
J Del Rowe et al.
JOURNAL OF CLINICAL ONCOLOGY (2000)