Related references
Note: Only part of the references are listed.Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS
Joanna J. Bury et al.
NEUROPATHOLOGY (2016)
Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS
Marc Suarez-Calvet et al.
ACTA NEUROPATHOLOGICA (2016)
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss
Jelena Scekic-Zahirovic et al.
EMBO JOURNAL (2016)
ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function
Aarti Sharma et al.
NATURE COMMUNICATIONS (2016)
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects
James R. Priest et al.
PLOS GENETICS (2016)
SnapShot: Genetics of ALS and FTD
Rita Guerreiro et al.
CELL (2015)
ALS mutations in TLS/FUS disrupt target gene expression
Tristan H. Coady et al.
GENES & DEVELOPMENT (2015)
Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import
Simona Darovic et al.
JOURNAL OF CELL SCIENCE (2015)
Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice
Owen M. Peters et al.
NEURON (2015)
C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD
Jacqueline G. O'Rourke et al.
NEURON (2015)
Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif
Hannah K. Robinson et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2015)
ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation
Andrew King et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis
Yoshihiro Kino et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Amyotrophic Lateral Sclerosis Onset Is Influenced by the Burden of Rare Variants in Known Amyotrophic Lateral Sclerosis Genes
Janet Cady et al.
ANNALS OF NEUROLOGY (2015)
Diagnosis and Management of Behavioral Variant Frontotemporal Dementia
Peter S. Pressman et al.
BIOLOGICAL PSYCHIATRY (2014)
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
Haiyan Qiu et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage
Qiudong Deng et al.
JOURNAL OF NEUROSCIENCE (2014)
Assessment of cognitive impairment in amyotrophic lateral sclerosis
F. J. Rodriguez de Rivera et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2014)
Frontotemporal dementia and its subtypes: a genome-wide association study
Raffaele Ferrari et al.
LANCET NEUROLOGY (2014)
The role of FUS gene variants in neurodegenerative diseases
Hao Deng et al.
NATURE REVIEWS NEUROLOGY (2014)
Activity-dependent FUS dysregulation disrupts synaptic homeostasis
Chantelle F. Sephton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Autosomal dominant inheritance of rapidly progressive amyotrophic lateral sclerosis due to a truncation mutation in the fused in sarcoma (FUS) gene
Louisa Kent et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2014)
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
Jacqueline C. Mitchell et al.
ACTA NEUROPATHOLOGICA (2013)
RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations
J. Gavin Daigle et al.
HUMAN MOLECULAR GENETICS (2013)
Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS
Gary A. B. Armstrong et al.
HUMAN MOLECULAR GENETICS (2013)
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
Caroline Vance et al.
HUMAN MOLECULAR GENETICS (2013)
The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
Adam S. Mastrocola et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice
Tatyana A. Shelkovnikova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
Wen-Yuan Wang et al.
NATURE NEUROSCIENCE (2013)
25 years of neuroimaging in amyotrophic lateral sclerosis
Bradley R. Foerster et al.
NATURE REVIEWS NEUROLOGY (2013)
The epidemiology of ALS: a conspiracy of genes, environment and time
Ammar Al-Chalabi et al.
NATURE REVIEWS NEUROLOGY (2013)
Deciphering amyotrophic lateral sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis
John Ravits et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2013)
The genetics and neuropathology of amyotrophic lateral sclerosis
Ammar Al-Chalabi et al.
ACTA NEUROPATHOLOGICA (2012)
The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum
Tim Van Langenhove et al.
ANNALS OF MEDICINE (2012)
How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders?
Marka van Blitterswijk et al.
CURRENT OPINION IN NEUROLOGY (2012)
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS
Dorothee Dormann et al.
EMBO JOURNAL (2012)
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism
Tetsuro Murakami et al.
HUMAN MOLECULAR GENETICS (2012)
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
Miranda L. Tradewell et al.
HUMAN MOLECULAR GENETICS (2012)
Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats
Cao Huang et al.
HUMAN MOLECULAR GENETICS (2012)
Evidence for an oligogenic basis of amyotrophic lateral sclerosis
Marka van Blitterswijk et al.
HUMAN MOLECULAR GENETICS (2012)
Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)
Eva Bentmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Familial ALS with FUS P525L mutation: two Japanese sisters with multiple systems involvement
Yoko Mochizuki et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2012)
Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis
Christophe Verbeeck et al.
MOLECULAR NEURODEGENERATION (2012)
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
Clotilde Lagier-Tourenne et al.
NATURE NEUROSCIENCE (2012)
VAPB and C9orf72 mutations in 1 familial amyotrophic lateral sclerosis patient
Marka van Blitterswijk et al.
NEUROBIOLOGY OF AGING (2012)
FUS and TDP43 genetic variability in FTD and CBS
Edward D. Huey et al.
NEUROBIOLOGY OF AGING (2012)
TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements
Adelene Y. Tan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Distinct pathological subtypes of FTLD-FUS
Ian R. A. Mackenzie et al.
ACTA NEUROPATHOLOGICA (2011)
Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation
Ian R. A. Mackenzie et al.
ACTA NEUROPATHOLOGICA (2011)
The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene
Julie S. Snowden et al.
ACTA NEUROPATHOLOGICA (2011)
Transportin1: a marker of FTLD-FUS
Jack Brelstaff et al.
ACTA NEUROPATHOLOGICA (2011)
The epidemiology and treatment of ALS: Focus on the heterogeneity of the disease and critical appraisal of therapeutic trials
Ettore Beghi et al.
AMYOTROPHIC LATERAL SCLEROSIS (2011)
TLS and PRMT1 synergistically coactivate transcription at the survivin promoter through TLS arginine methylation
Kun Du et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
Katya Rascovsky et al.
BRAIN (2011)
A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43
Nicholas A. Lanson et al.
HUMAN MOLECULAR GENETICS (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
A Yeast Model of FUS/TLS-Dependent Cytotoxicity
Shulin Ju et al.
PLOS BIOLOGY (2011)
FUS and TARDBP but Not SOD1 Interact in Genetic Models of Amyotrophic Lateral Sclerosis
Edor Kabashi et al.
PLOS GENETICS (2011)
FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
Cao Huang et al.
PLOS GENETICS (2011)
Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation
Takahisa Tateishi et al.
ACTA NEUROPATHOLOGICA (2010)
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update
Ian R. A. Mackenzie et al.
ACTA NEUROPATHOLOGICA (2010)
Extensive FUS-Immunoreactive Pathology in Juvenile Amyotrophic Lateral Sclerosis with Basophilic Inclusions
Eric J. Huang et al.
BRAIN PATHOLOGY (2010)
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
Daryl A. Bosco et al.
HUMAN MOLECULAR GENETICS (2010)
Mutations of FUS gene in sporadic amyotrophic lateral sclerosis
Lucia Corrado et al.
JOURNAL OF MEDICAL GENETICS (2010)
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
Ian R. A. Mackenzie et al.
LANCET NEUROLOGY (2010)
FUS GENE MUTATIONS IN FAMILIAL AND SPORADIC AMYOTROPHIC LATERAL SCLEROSIS
Rosa Rademakers et al.
MUSCLE & NERVE (2010)
Genetic contribution of FUS to frontotemporal lobar degeneration
T. Van Langenhove et al.
NEUROLOGY (2010)
Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations
D. Baeumer et al.
NEUROLOGY (2010)
Oligogenic basis of isolated gonadotropin-releasing hormone deficiency
Gerasimos P. Sykiotis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome
Norann A. Zaghloul et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease
Manuela Neumann et al.
ACTA NEUROPATHOLOGICA (2009)
FUS pathology in basophilic inclusion body disease
David G. Munoz et al.
ACTA NEUROPATHOLOGICA (2009)
A new subtype of frontotemporal lobar degeneration with FUS pathology
Manuela Neumann et al.
BRAIN (2009)
Protein Arginine Methylation in Mammals: Who, What, and Why
Mark T. Bedford et al.
MOLECULAR CELL (2009)
Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort
N. Ticozzi et al.
NEUROLOGY (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
T. J. Kwiatkowski et al.
SCIENCE (2009)
TDP-43 A315T mutation in familial motor neuron disease
Michael A. Gitcho et al.
ANNALS OF NEUROLOGY (2008)
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
Mattias K. Andersson et al.
BMC CELL BIOLOGY (2008)
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
Jemeen Sreedharan et al.
SCIENCE (2008)
Basophilic inclusion body disease and neuronal intermediate filament inclusion disease: a comparative clinicopathological study
Osamu Yokota et al.
ACTA NEUROPATHOLOGICA (2008)
Cognitive impairment in amyotrophic lateral sclerosis
Julie Phukan et al.
LANCET NEUROLOGY (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: common pathways in neurodegenerative disease
Kevin Talbot et al.
HUMAN MOLECULAR GENETICS (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
The effects of executive and behavioral dysfunction on the course of ALS
RK Olney et al.
NEUROLOGY (2005)
Oligogenic combinations associated with breast cancer risk in women under 53 years of age
CE Aston et al.
HUMAN GENETICS (2005)
Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode
J Rappsilber et al.
ANALYTICAL CHEMISTRY (2003)
Clinical trials in ALS: An overview
MR Turner et al.
SEMINARS IN NEUROLOGY (2001)
Serum and cerebrospinal fluid biochemical markers of ALS
PJ Shaw et al.
AMYOTROPHIC LATERAL SCLEROSIS (2000)
Male sterility and enhanced radiation sensitivity in TLS-/- mice
M Kuroda et al.
EMBO JOURNAL (2000)
Confounding effects of mimicking disorders in the early diagnosis of amyotrophic lateral sclerosis
JH Wokke
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS (2000)
Share Paper
