Advanced Nanocomposite Hydrogels for Cartilage Tissue Engineering

Tissue engineering is becoming an effective strategy for repairing cartilage damage. Synthesized nanocomposite hydrogels mimic the structure of natural cartilage extracellular matrices (ECMs), are biocompatible, and exhibit nano-bio effects in response to external stimuli. These inherent characteristics make nanocomposite hydrogels promising scaffold materials for cartilage tissue engineering. This review summarizes the advances made in the field of nanocomposite hydrogels for artificial cartilage. We discuss, in detail, their preparation methods and scope of application. The challenges involved for the application of hydrogel nanocomposites for cartilage repair are also highlighted.

Automated summary

Nanocomposite hydrogels, with their ability to mimic natural cartilage structure and exhibit nano-bio effects in response to external stimuli, show great potential as scaffold materials for cartilage tissue engineering. This review article summarizes the recent advances in nanocomposite hydrogels for artificial cartilage, including their preparation methods and application scope, while also highlighting the challenges faced in using hydrogel nanocomposites for cartilage repair.