Related references
Note: Only part of the references are listed.Shuttling of PINK1 between Mitochondrial Microcompartments Resolved by Triple-Color Superresolution Microscopy
Felix R. M. Beinlich et al.
ACS CHEMICAL BIOLOGY (2015)
Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signaling pathways
Dana Fallaize et al.
CELLULAR SIGNALLING (2015)
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis
Atul Kumar et al.
EMBO JOURNAL (2015)
A Ubl/ubiquitin switch in the activation of Parkin
Veronique Sauve et al.
EMBO JOURNAL (2015)
Phosphorylation of ubiquitin at Ser65 affects its polymerization, targets, and proteome-wide turnover
Danielle L. Swaney et al.
EMBO REPORTS (2015)
(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation
Fabienne C. Fiesel et al.
EMBO REPORTS (2015)
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
Agne Kazlauskaite et al.
EMBO REPORTS (2015)
Phosphorylated ubiquitin chain is the genuine Parkin receptor
Kei Okatsu et al.
JOURNAL OF CELL BIOLOGY (2015)
Mechanism of phospho-ubiquitin-induced PARKIN activation
Tobias Wauer et al.
NATURE (2015)
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Michael Lazarou et al.
NATURE (2015)
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
Alicia M. Pickrell et al.
NEURON (2015)
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy
Alban Ordureau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
Tobias Wauer et al.
EMBO JOURNAL (2015)
PINK1 Kinase Catalytic Activity Is Regulated by Phosphorylation on Serines 228 and 402
Liesbeth Aerts et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
Agne Kazlauskaite et al.
BIOCHEMICAL JOURNAL (2014)
USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin
Thomas M. Durcan et al.
EMBO JOURNAL (2014)
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
Tom Cornelissen et al.
HUMAN MOLECULAR GENETICS (2014)
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Lesley A. Kane et al.
JOURNAL OF CELL BIOLOGY (2014)
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
Alban Ordureau et al.
MOLECULAR CELL (2014)
PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
Vanessa A. Morais et al.
SCIENCE (2014)
Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling
Kirti Sharma et al.
CELL REPORTS (2014)
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Agne Kazlauskaite et al.
OPEN BIOLOGY (2014)
Therapeutic Prospects for Parkinson Disease
C. Warren Olanow et al.
ANNALS OF NEUROLOGY (2013)
PINK1 is degraded through the N-end rule pathway
Koji Yamano et al.
AUTOPHAGY (2013)
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
Seok Min Jin et al.
AUTOPHAGY (2013)
Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease
Heather Mortiboys et al.
BRAIN (2013)
A Neo-Substrate that Amplifies Catalytic Activity of Parkinson's-Disease-Related Kinase PINK1
Nicholas T. Hertz et al.
CELL (2013)
Structure of the human Parkin ligase domain in an autoinhibited state
Tobias Wauer et al.
EMBO JOURNAL (2013)
PINK1 rendered temperature sensitive by disease-associated and engineered mutations
Derek P. Narendra et al.
HUMAN MOLECULAR GENETICS (2013)
A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment
Kei Okatsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
Shireen A. Sarraf et al.
NATURE (2013)
100 years of Lewy pathology
Michel Goedert et al.
NATURE REVIEWS NEUROLOGY (2013)
Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
Jean-Francois Trempe et al.
SCIENCE (2013)
The Ubiquitin Code
David Komander et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
Michael Lazarou et al.
DEVELOPMENTAL CELL (2012)
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
Andrew W. Greene et al.
EMBO REPORTS (2012)
Analysis of the Regulatory and Catalytic Domains of PTEN-Induced Kinase-1 (PINK1)
Chou Hung Sim et al.
HUMAN MUTATION (2012)
Pink1 Kinase and Its Membrane Potential (Δψ)-dependent Cleavage Product Both Localize to Outer Mitochondrial Membrane by Unique Targeting Mode
Dorothea Becker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency
Melissa Vos et al.
SCIENCE (2012)
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Alicia Lundby et al.
NATURE COMMUNICATIONS (2012)
PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
Kei Okatsu et al.
NATURE COMMUNICATIONS (2012)
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
Kahori Shiba-Fukushima et al.
SCIENTIFIC REPORTS (2012)
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
Chandana Kondapalli et al.
OPEN BIOLOGY (2012)
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Emma Deas et al.
HUMAN MOLECULAR GENETICS (2011)
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
Nickie C. Chan et al.
HUMAN MOLECULAR GENETICS (2011)
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
Cathrin Meissner et al.
JOURNAL OF NEUROCHEMISTRY (2011)
The Intermembrane Space of Mitochondria
Johannes M. Herrmann et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
Sven Geisler et al.
AUTOPHAGY (2010)
Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-κB signaling
Di Sha et al.
HUMAN MOLECULAR GENETICS (2010)
Parkinson's disease: insights from pathways
Mark R. Cookson et al.
HUMAN MOLECULAR GENETICS (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Seok Min Jin et al.
JOURNAL OF CELL BIOLOGY (2010)
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
Noriyuki Matsuda et al.
JOURNAL OF CELL BIOLOGY (2010)
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Sven Geisler et al.
NATURE CELL BIOLOGY (2010)
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
Cristofol Vives-Bauza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Derek P. Narendra et al.
PLOS BIOLOGY (2010)
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
Francisca E. Reyes-Turcu et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Aggresome Formation and Neurodegenerative Diseases: Therapeutic Implications
L. Chin et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)
Ryan D. Mills et al.
JOURNAL OF NEUROCHEMISTRY (2008)
The kinase domain of mitochondrial PINK1 faces the cytoplasm
Chun Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
Helene Plun-Favreau et al.
NATURE CELL BIOLOGY (2007)
Pathogenic mutations in Parkinson disease
Eng-King Tan et al.
HUMAN MUTATION (2007)
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
Julia W. Pridgeon et al.
PLOS BIOLOGY (2007)
PINK1 mutation heterozygosity and the risk of Parkinson's disease
M. Toft et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2007)
Mitochondria: More than just a powerhouse
Heidi M. McBride et al.
CURRENT BIOLOGY (2006)
Diagnosis and treatment of Parkinson disease: molecules to medicine
Joseph M. Savitt et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress
Miratul M. K. Muqit et al.
JOURNAL OF NEUROCHEMISTRY (2006)
PINK1 protein in normal human brain and Parkinson's disease
S. Gandhi et al.
BRAIN (2006)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
Homozygous and heterozygous PINKI mutations:: Considerations for diagnosis and care of Parkinson's disease patients
Cindy Zadikoff et al.
MOVEMENT DISORDERS (2006)
Clinical spectrum of homozygous and heterozygous PINK1 mutations in a large German family with Parkinson disease : Role of a single hit?
Katja Hedrich et al.
ARCHIVES OF NEUROLOGY (2006)
Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism
L Silvestri et al.
HUMAN MOLECULAR GENETICS (2005)
Dopamine covalently modifies and functionally inactivates parkin
MJ LaVoie et al.
NATURE MEDICINE (2005)
Early-onset parkinsonism associated with PINK1 mutations -: Frequency, genotypes, and phenotypes
V Bonifati et al.
NEUROLOGY (2005)
Novel PINK1 mutations in early-onset parkinsonism
Y Hatano et al.
ANNALS OF NEUROLOGY (2004)
Pathogenetic mechanisms of parkin in Parkinson's disease
N Hattori et al.
LANCET (2004)
Nitrosative stress linked to sporadic Parkinson's disease:: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
DD Yao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Stages in the development of Parkinson's disease-related pathology
H Braak et al.
CELL AND TISSUE RESEARCH (2004)
S-nitrosylation of Parkin regulates ubiquitination and compromises Parkin's protective function
KKK Chung et al.
SCIENCE (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
A proteomics approach to understanding protein ubiquitination
JM Peng et al.
NATURE BIOTECHNOLOGY (2003)
Themes and variations on ubiquitylation
AM Weissman
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Share Paper
