Polymeric Matrix-Based Nanoplatforms toward Tumor Therapy and Diagnosis

Flexible polymeric matrixes containing microneedles (MNs), hydrogels, and microcapsules/microspheres have received considerable attention and hold great promise for biomedical applications as delivery systems owing to their superior biocompatibility and biodegradation, excellent patient compliance, and high loading capability. The integration of nanomaterial systems endows polymeric patches with some optimized properties including improved therapeutic efficacy and lowered systemic toxicity, facilitating on-demand and controllable drug delivery, thus extremely expanding their bioapplication. This review briefly summarizes the recent progress of flexible polymeric patches integrated with nanomaterial systems as a delivery approach for tumor therapeutics. In addition, the current challenges, limitations, and future prospects of such therapeutic devices in biomedicine are also discussed.

Automated summary

Flexible polymeric patches integrated with nanomaterial systems have made significant progress as a delivery approach for tumor therapeutics, offering improved therapeutic efficacy and reduced systemic toxicity. This technology enables on-demand and controllable drug delivery.