4.5 Article

Microtubule disruption reduces metastasis more effectively than primary tumor growth

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin

Takashi Hotta et al.

Summary: The translation discusses the importance of detyrosination as a post-translational modification of microtubules and the use of parthenolide to block this process. It also highlights the efficacy of epoY as an alternative inhibitor of microtubule detyrosination.

CURRENT BIOLOGY (2021)

Article Oncology

FDA Approval Summary: Accelerated Approval of Sacituzumab Govitecan-hziy for Third-line Treatment of Metastatic Triple-negative Breast Cancer

Sakar Wahby et al.

Summary: FDA granted accelerated approval to Sacituzumab Govitecan-hziy for the treatment of metastatic triple-negative breast cancer. Data showed an objective response rate of 33.3% and a median duration of response of 7.7 months, supporting the approval.

CLINICAL CANCER RESEARCH (2021)

Review Oncology

Liquid biopsy and minimal residual disease - latest advances and implications for cure

Klaus Pantel et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Article Engineering, Biomedical

A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens

Christopher L. Yankaskas et al.

NATURE BIOMEDICAL ENGINEERING (2019)

Article Biochemistry & Molecular Biology

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

Sofia Gkountela et al.

Review Oncology

A framework for the development of effective anti-metastatic agents

Robin L. Anderson et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Article Oncology

Black race and distant recurrence after neoadjuvant or adjuvant chemotherapy in breast cancer

Jessica M. Pastoriza et al.

CLINICAL & EXPERIMENTAL METASTASIS (2018)

Article Oncology

Cytoskeletal organization in microtentacles

Alison N. Killilea et al.

EXPERIMENTAL CELL RESEARCH (2017)

Article Oncology

Current Update of Patient-Derived Xenograft Model for Translational Breast Cancer Research

Tsutomu Kawaguchi et al.

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2017)

Article Cell Biology

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

George S. Karagiannis et al.

SCIENCE TRANSLATIONAL MEDICINE (2017)

Article Chemistry, Multidisciplinary

Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer

Ramakrishna Samala et al.

PHARMACEUTICAL RESEARCH (2016)

Article Biochemistry & Molecular Biology

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

Nicola Aceto et al.

Article Biochemical Research Methods

Size-selective collection of circulating tumor cells using Vortex technology

Elodie Sollier et al.

LAB ON A CHIP (2014)

Review Pathology

Breast Cancer Metastasis Issues for the Personalization of Its Prevention and Treatment

Natascia Marino et al.

AMERICAN JOURNAL OF PATHOLOGY (2013)

Article Biophysics

Analysis of multiple physical parameters for mechanical phenotyping of living cells

T. R. Kiessling et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2013)

Article Oncology

Response-Guided Neoadjuvant Chemotherapy for Breast Cancer

Gunter von Minckwitz et al.

JOURNAL OF CLINICAL ONCOLOGY (2013)

Article Biochemistry & Molecular Biology

Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin

M. I. Vitolo et al.

ONCOGENE (2013)

Article Medicine, Research & Experimental

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

Brian D. Lehmann et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Oncology

Microtentacles Tip the Balance of Cytoskeletal Forces in Circulating Tumor Cells

Michael A. Matrone et al.

CANCER RESEARCH (2010)

Article Biochemistry & Molecular Biology

c-Src differentially regulates the functions of microtentacles and invadopodia

E. M. Balzer et al.

ONCOGENE (2010)

Article Oncology

Detyrosinated microtubule protrusions in suspended mammary epithelial cells promote reattachment

Rebecca A. Whipple et al.

EXPERIMENTAL CELL RESEARCH (2007)

Article Medicine, General & Internal

Circulating tumor cells, disease progression, and survival in metastatic breast cancer

M Cristofanilli et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)