4.3 Article

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR): A critical overview on the most promising applications of molecular scissors in oral medicine

Journal

BIOCELL
Volume 46, Issue 8, Pages 1837-1842

Publisher

TECH SCIENCE PRESS
DOI: 10.32604/biocell.2022.020570

Keywords

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR); Dentistry; Stem cells

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The CRISPR-Cas9 system is a biotechnology that improves the efficacy of traditional treatments, particularly in the field of oral medicine. By speeding up and customizing therapies, this technology enhances the predictability of clinical outcomes and opens up new possibilities for treating oral diseases.
The scientific community is continuously working to translate the novel biomedical techniques into effective medical treatments. CRISPR-Cas 9 system (Clustered Regularly Interspaced Short Palindromic Repeats-9), commonly known as the molecular scissor, represents a recently developed biotechnology able to improve the quality and the efficacy of traditional treatments, related to several human diseases, such as chronic diseases, neurodegenerative pathologies and, interestingly, oral diseases. Of course, dental medicine has notably increased the use of biotechnologies to ensure modern and conservative approaches: in this landscape, the use of CRISPR-Cas-9 system may speed and personalize the traditional therapies, ensuring a good predictability of clinical results. The aim of this critical overview is to provide evidence on CRISPR efficacy, taking into specific account its applications in oral medicine.

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