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Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence
Diamantis I. Tsilimigras et al.
SURGICAL ONCOLOGY-OXFORD (2018)
Circulating Exosomal miR-17-5p and miR-92a-3p Predict Pathologic Stage and Grade of Colorectal Cancer
Fangfang Fu et al.
TRANSLATIONAL ONCOLOGY (2018)
LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1
Yujia Shan et al.
CELL DEATH & DISEASE (2018)
Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
Sean P. Pitroda et al.
NATURE COMMUNICATIONS (2018)
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
Tomer Cooks et al.
NATURE COMMUNICATIONS (2018)
Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer
Georgios Antonios Margonis et al.
JAMA SURGERY (2018)
Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer
Guoying Zhou et al.
ONCOIMMUNOLOGY (2018)
Ultra-high FRET efficiency NaGdF4: Tb3+-Rose Bengal biocompatible nanocomposite for X-ray excited photodynamic therapy application
Wenli Zhang et al.
BIOMATERIALS (2018)
Exosomes from BM-MSCs increase the population of CSCs via transfer of miR-142-3p
Hongdan Li et al.
BRITISH JOURNAL OF CANCER (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases
Jiaxin Liang et al.
CANCER RESEARCH (2018)
Colorectal cancer-derived small extracellular vesicles establish an inflammatory premetastatic niche in liver metastasis
Yingkuan Shao et al.
CARCINOGENESIS (2018)
Efficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial
Shukui Qin et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
Prognostic Impact of miR-200 Family Members in Plasma and Exosomes from Tumor-Draining versus Peripheral Veins of Colon Cancer Patients
Sandra Santasusagna et al.
ONCOLOGY (2018)
A comprehensive look at the role of hyperlipidemia in promoting colorectal cancer liver metastasis
Yimin Shen et al.
JOURNAL OF CANCER (2018)
GNA13 promotes tumor growth and angiogenesis by upregulating CXC chemokines via the NF-κB signaling pathway in colorectal cancer cells
Zhongqiang Zhang et al.
CANCER MEDICINE (2018)
Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer
Julie G. Grossman et al.
ONCOIMMUNOLOGY (2018)
Trapping of Lipopolysaccharide to Promote Immunotherapy against Colorectal Cancer and Attenuate Liver Metastasis
Wantong Song et al.
ADVANCED MATERIALS (2018)
Long noncoding RNA B3GALT5-AS1 suppresses colon cancer liver metastasis via repressing microRNA-203
Liang Wang et al.
AGING-US (2018)
Role of Endoglin (CD105) in the Progression of Hepatocellular Carcinoma and Anti-Angiogenic Therapy
Aldona Kasprzak et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer
Marjorie De la Fuente López et al.
TUMOR BIOLOGY (2018)
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis
Zhicheng Zeng et al.
NATURE COMMUNICATIONS (2018)
Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix
A. E. Yuzhalin et al.
NATURE COMMUNICATIONS (2018)
Apolipoprotein E Overexpression Is Associated With Tumor Progression and Poor Survival in Colorectal Cancer
Zhixun Zhao et al.
FRONTIERS IN GENETICS (2018)
Is there a survival benefit from adjuvant chemotherapy for patients with liver oligometastases from colorectal cancer after curative resection?
Zhizhong Pan et al.
CANCER COMMUNICATIONS (2018)
Effect of bevacizumab plus XELOX (CapeOX) chemotherapy on liver natural killer cell activity in colorectal cancer with resectable liver metastasis
Fumihiro Hirata et al.
ANNALS OF GASTROENTEROLOGICAL SURGERY (2018)
The diverse functions of the PD1 inhibitory pathway
Arlene H. Sharpe et al.
NATURE REVIEWS IMMUNOLOGY (2018)
Regulatory T cells in cancer immunotherapy
Atsushi Tanaka et al.
CELL RESEARCH (2017)
Circulating tumour cells from patients with colorectal cancer have cancer stem cell hallmarks in ex vivo culture
Fanny Grillet et al.
GUT (2017)
Tumour CD274 (PD-L1) expression and T cells in colorectal cancer
Yohei Masugi et al.
GUT (2017)
Identification of microRNA-487b as a negative regulator of liver metastasis by regulation of KRAS in colorectal cancer
Tsuyoshi Hata et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis
Yu Zhang et al.
MOLECULAR CARCINOGENESIS (2017)
LPS-induced CXCR4-dependent migratory properties and a mesenchymal-like phenotype of colorectal cancer cells
Wen-Ting Liu et al.
CELL ADHESION & MIGRATION (2017)
p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription
Liang Zhong et al.
ONCOTARGET (2017)
Antagonistic Effects of p53 and HIF1A on microRNA-34a Regulation of PPP1R11 and STAT3 and Hypoxia-induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells
Huihui Li et al.
GASTROENTEROLOGY (2017)
P53-induced miR-30e-5p inhibits colorectal cancer invasion and metastasis by targeting ITGA6 and ITGB1
Sara Laudato et al.
INTERNATIONAL JOURNAL OF CANCER (2017)
PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism
Heyang Xu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Effect of First-Line Chemotherapy Combined With Cetuximab or Bevacizumab on Overall Survival in Patients With KRAS Wild-Type Advanced or Metastatic Colorectal Cancer A Randomized Clinical Trial
Alan P. Venook et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)
MicroRNA-30a-5p (miR-30a) regulates cell motility and EMT by directly targeting oncogenic TM4SF1 in colorectal cancer
Y. R. Park et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2017)
Exosomes-mediated transfer of long noncoding RNA ZFAS1 promotes gastric cancer progression
Lei Pan et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2017)
Increased Infiltration of Natural Killer and T Cells in Colorectal Liver Metastases Improves Patient Overall Survival
Matteo Donadon et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2017)
Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways
Jingkun Zhao et al.
MOLECULAR CANCER (2017)
Correlation analysis between liver metastasis and serum levels of miR-200 and miR-141 in patients with colorectal cancer
Meng Ding et al.
MOLECULAR MEDICINE REPORTS (2017)
Determinants of metastatic competency in colorectal cancer
Daniele V. F. Tauriello et al.
MOLECULAR ONCOLOGY (2017)
A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
Felipe de Sousa e Melo et al.
NATURE (2017)
Visualization and targeting of LGR5+ human colon cancer stem cells
Mariko Shimokawa et al.
NATURE (2017)
Tumour-associated macrophages as treatment targets in oncology
Alberto Mantovani et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis
E. Agarwal et al.
ONCOGENE (2017)
Current status and future perspectives on treatment of liver metastasis in colorectal cancer (Review)
Mahdi Hussain Al Bandar et al.
ONCOLOGY REPORTS (2017)
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
Dung T. Le et al.
SCIENCE (2017)
Mechanisms that drive inflammatory tumor microenvironment, tumor heterogeneity, and metastatic progression
Li Yang et al.
SEMINARS IN CANCER BIOLOGY (2017)
Role of miRNAs in human cancer metastasis: Implications for therapeutic intervention
Mohammad Alam Jafri et al.
SEMINARS IN CANCER BIOLOGY (2017)
miR-133a acts as a tumor suppressor in colorectal cancer by targeting eIF4A1
Wenfeng Li et al.
TUMOR BIOLOGY (2017)
Decrease of miR-622 expression suppresses migration and invasion by targeting regulation of DYRK2 in colorectal cancer cells
Yong Wang et al.
ONCOTARGETS AND THERAPY (2017)
Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer
Yang Li et al.
CELL DEATH & DISEASE (2017)
miR-10a suppresses colorectal cancer metastasis by modulating the epithelial-to-mesenchymal transition and anoikis
Yankun Liu et al.
CELL DEATH & DISEASE (2017)
MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression
Yun Teng et al.
NATURE COMMUNICATIONS (2017)
Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer
Colin Siu-Chi Lam et al.
ONCOTARGET (2017)
Circular RNA hsa_circ_000984 promotes colon cancer growth and metastasis by sponging miR-106b
Xiao-Wu Xu et al.
ONCOTARGET (2017)
Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression
Dong-liang Chen et al.
THERANOSTICS (2017)
Myeloid-Derived Suppressor Cells
Dmitry I. Gabrilovich
CANCER IMMUNOLOGY RESEARCH (2017)
Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC
Paul C. Tumeh et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Prognostic value of CD133+CD54+CD44+ circulating tumor cells in colorectal cancer with liver metastasis
Chao Fang et al.
CANCER MEDICINE (2017)
Exploration of Graphitic-C3N4 Quantum Dots for Microwave-Induced Photodynamic Therapy
Xiao Chu et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Exploration of Graphitic-C3N4 Quantum Dots for Microwave-Induced Photodynamic Therapy
Xiao Chu et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Activation of the mTOR Pathway by Oxaliplatin in the Treatment of Colorectal Cancer Liver Metastasis
Min Lu et al.
PLOS ONE (2017)
Investigation of Copper Cysteamine Nanoparticles as a New Type of Radiosensitiers for Colorectal Carcinoma Treatment
Zhipeng Liu et al.
SCIENTIFIC REPORTS (2017)
miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5
Verena Stiegelbauer et al.
CLINICAL CANCER RESEARCH (2017)
CXCL1 Is Critical for Premetastatic Niche Formation and Metastasis in Colorectal Cancer
Dingzhi Wang et al.
CANCER RESEARCH (2017)
tRF/miR-1280 Suppresses Stem Cell-like Cells and Metastasis in Colorectal Cancer
Bingqing Huang et al.
CANCER RESEARCH (2017)
Pre-metastatic niches: organ-specific homes for metastases
Hector Peinado et al.
NATURE REVIEWS CANCER (2017)
Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis
Kuei-Yang Hsiao et al.
CANCER RESEARCH (2017)
Global Cancer Incidence and Mortality Rates and Trends-An Update
Lindsey A. Torre et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2016)
Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis
Cheng Xing et al.
CANCER RESEARCH (2016)
Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15-CCR1 Chemokine Axis
Susumu Inamoto et al.
CLINICAL CANCER RESEARCH (2016)
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis
Hui Ling et al.
GUT (2016)
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer
John J. Arcaroli et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Down-Regulation of microRNA-132 is Associated with Poor Prognosis of Colorectal Cancer
Yukako Mokutani et al.
ANNALS OF SURGICAL ONCOLOGY (2016)
Exosomes secreted from human colon cancer cells influence the adhesion of neighboring metastatic cells: Role of microRNA-210
Elisabetta Bigagli et al.
CANCER BIOLOGY & THERAPY (2016)
Circulating Long RNAs in Serum Extracellular Vesicles: Their Characterization and Potential Application as Biomarkers for Diagnosis of Colorectal Cancer
Lei Dong et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2016)
Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress
Samer Tohme et al.
CANCER RESEARCH (2016)
microRNA-497 inhibits invasion and metastasis of colorectal cancer cells by targeting vascular endothelial growth factor-A
Yanyan Qiu et al.
CELL PROLIFERATION (2016)
PD-1/PD-L and autoimmunity: A growing relationship
Mohammad Reza Zamani et al.
CELLULAR IMMUNOLOGY (2016)
Overcoming the Achilles' heel of photodynamic therapy
Wenpei Fan et al.
CHEMICAL SOCIETY REVIEWS (2016)
Therapeutic Strategies in Diseases of the Digestive Tract-2015 and Beyond Targeted Therapies in Colon Cancer Today and Tomorrow
Michael Pohl et al.
DIGESTIVE DISEASES (2016)
Selection for surgery and survival of synchronous colorectal liver metastases; a nationwide study
A. Noren et al.
EUROPEAN JOURNAL OF CANCER (2016)
The Role of Chemokines in Promoting Colorectal Cancer Invasion/Metastasis
Yoshiro Itatani et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
A New Modality for Cancer Treatment-Nanoparticle Mediated Microwave Induced Photodynamic Therapy
Mengyu Yao et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2016)
The biology and function of exosomes in cancer
Raghu Kalluri
JOURNAL OF CLINICAL INVESTIGATION (2016)
Cell elasticity with altered cytoskeletal architectures across multiple cell types
Martha E. Grady et al.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2016)
Exosomes in colorectal carcinoma formation: ALIX under the magnifying glass
Gabor Valcz et al.
MODERN PATHOLOGY (2016)
Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer
M. Paauwe et al.
ONCOGENE (2016)
MiRNA-21 Expression Decreases from Primary Tumors to Liver Metastases in Colorectal Carcinoma
Fabian Feiersinger et al.
PLOS ONE (2016)
Inhibition of miR-15b decreases cell migration and metastasis in colorectal cancer
Jian Li et al.
TUMOR BIOLOGY (2016)
miR-497 suppresses epithelial-mesenchymal transition and metastasis in colorectal cancer cells by targeting fos-related antigen-1
Nan Zhang et al.
ONCOTARGETS AND THERAPY (2016)
Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury
Subhrajit Saha et al.
NATURE COMMUNICATIONS (2016)
Incidence and origin of histologically confirmed liver metastases: an explorative case-study of 23,154 patients
Jannemarie de Ridder et al.
ONCOTARGET (2016)
Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression
Nami Yamada et al.
ONCOTARGET (2016)
MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4
Dantong Cheng et al.
ONCOTARGET (2016)
modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient
Imran Siddiqui et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2016)
A Non-rare-Earth Ions Self-Activated White Emitting Phosphor under Single Excitation
Hongyu Guo et al.
ADVANCED FUNCTIONAL MATERIALS (2015)
Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression
Qing Ji et al.
BMC CANCER (2015)
Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer
T. Matsumura et al.
BRITISH JOURNAL OF CANCER (2015)
Metastatic colonization of the liver by colorectal tumor cells is abolished by two micro-RNAs (nniR-483-5p et miR-551a)
Christian-Jacques Larsen
BULLETIN DU CANCER (2015)
Global Cancer Statistics, 2012
Lindsey A. Torre et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2015)
Immunohistochemical expression of Notch1, Jagged1, NF-κB and MMP-9 in colorectal cancer patients and the relationship to clinicopathological parameters
Chen-Guo Zheng et al.
CANCER BIOMARKERS (2015)
Tumor microenvironment: Sanctuary of the devil
Lanlan Hui et al.
CANCER LETTERS (2015)
Managing synchronous liver metastases from colorectal cancer: A multidisciplinary international consensus
Rene Adam et al.
CANCER TREATMENT REVIEWS (2015)
Extracellular Metabolic Energetics Can Promote Cancer Progression
Jia Min Loo et al.
CELL (2015)
Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice
Dingzhi Wang et al.
GASTROENTEROLOGY (2015)
Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer
Alexander W. Fender et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
Intra-tumoural vessel area estimated by expression of epidermal growth factor-like domain 7 and microRNA-126 in primary tumours and metastases of patients with colorectal cancer: a descriptive study
Torben Frostrup Hansen et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
miR-19-Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal Cancer
D. Cellura et al.
MOLECULAR CANCER RESEARCH (2015)
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
D. T. Le et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Aberrant expression of long noncoding RNAs in colorectal cancer with liver metastasis
Le-chi Ye et al.
TUMOR BIOLOGY (2015)
miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR
Wenhua Li et al.
ONCOTARGET (2015)
The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer
Wei-Cheng Liang et al.
ONCOTARGET (2015)
GITR engagement in combination with CTLA-4 blockade completely abrogates immunosuppression mediated by human liver tumor-derived regulatory T cells ex vivo
Alexander Pedroza-Gonzalez et al.
ONCOIMMUNOLOGY (2015)
Colorectal cancer
Ernst J. Kuipers et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
Does the Primary Site of Colorectal Cancer Impact Outcomes for Patients With Metastatic Disease?
Timothy J. Price et al.
CANCER (2015)
Tissue Inhibitor of Metalloproteinases (TIMP)-1 Creates a Premetastatic Niche in the Liver Through SDF-1/CXCR4-Dependent Neutrophil Recruitment in Mice
Bastian Seubert et al.
HEPATOLOGY (2015)
被撤回的出版物: FOXC2 promotes colorectal cancer metastasis by directly targeting MET (Retracted article. See vol. 41, pg. 2529, 2022)
Y-M Cui et al.
ONCOGENE (2015)
PD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trials
Jason Madore et al.
PIGMENT CELL & MELANOMA RESEARCH (2015)
The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Nicolas J. Llosa et al.
CANCER DISCOVERY (2015)
The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis
Christina Therkildsen et al.
ACTA ONCOLOGICA (2014)
Metastatic pattern in colorectal cancer is strongly influenced by histological subtype
N. Hugen et al.
ANNALS OF ONCOLOGY (2014)
miR-30b regulates migration and invasion of human colorectal cancer via
Hui Zhao et al.
BIOCHEMICAL JOURNAL (2014)
p53-Induced miR-15a/16-1 and AP4 Form a Double-Negative Feedback Loop to Regulate Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer
Lei Shi et al.
CANCER RESEARCH (2014)
NOTCH3 Signaling Regulates MUSASHI-1 Expression in Metastatic Colorectal Cancer Cells
Anna Pasto et al.
CANCER RESEARCH (2014)
Colorectal Cancer Stem Cells: From the Crypt to the Clinic
Ann Zeuner et al.
CELL STEM CELL (2014)
Intratumoral regulatory T cells are associated with suppression of colorectal carcinoma metastasis after resection through overcoming IL-17 producing T cells
Quanrongzi Wang et al.
CELLULAR IMMUNOLOGY (2014)
CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis
Hideyo Hirai et al.
CLINICAL & EXPERIMENTAL METASTASIS (2014)
Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy
Janis M. Taube et al.
CLINICAL CANCER RESEARCH (2014)
Identification of MicroRNA-214 as a Negative Regulator of Colorectal Cancer Liver Metastasis by Way of Regulation of Fibroblast Growth Factor Receptor 1 Expression
Dong-liang Chen et al.
HEPATOLOGY (2014)
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J. Murray et al.
IMMUNITY (2014)
Downregulation of miR-214 is specific of liver metastasis in colorectal cancer and could play a role determining the metastatic niche
Ion Cristobal et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2014)
A New X-Ray Activated Nanoparticle Photosensitizer for Cancer Treatment
Lun Ma et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2014)
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
Matjaz Rokavec et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1
Dengbo Ji et al.
MOLECULAR CANCER (2014)
Panitumumab versus cetuximab in patients with chemotherapy-refractory wild-type KRAS exon 2 metastatic colorectal cancer (ASPECCT): a randomised, multicentre, open-label, non-inferiority phase 3 study
Timothy J. Price et al.
LANCET ONCOLOGY (2014)
The incidence of mismatch repair gene defects in colorectal liver metastases
Raul Alvarado-Bachmann et al.
MOLECULAR MEDICINE REPORTS (2014)
X-ray-induced nanoparticle-based photodynamic therapy of cancer
Xiaoju Zou et al.
NANOMEDICINE (2014)
Mechanotransduction and extracellular matrix homeostasis
Jay D. Humphrey et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
MicroRNA-497 and bufalin act synergistically to inhibit colorectal cancer metastasis
Yan-yan Qiu et al.
TUMOR BIOLOGY (2014)
Role of surgery in colorectal cancer liver metastases
Ozgur Akgul et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer
Y. Dai et al.
CELL DEATH & DISEASE (2014)
MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1
Mingxu Song et al.
PROTEIN & CELL (2014)
Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer
Morten Hagness et al.
ANNALS OF SURGERY (2013)
MACC1 mRNA Levels Predict Cancer Recurrence After Resection of Colorectal Cancer Liver Metastases
Claudio Isella et al.
ANNALS OF SURGERY (2013)
MiR-429 is an independent prognostic factor in colorectal cancer and exerts its anti-apoptotic function by targeting SOX2
Juan Li et al.
CANCER LETTERS (2013)
Increased LEF1 Expression and Decreased Notch2 Expression Are Strong Predictors of Poor Outcomes in Colorectal Cancer Patients
Wen-Juan Wang et al.
DISEASE MARKERS (2013)
Genetic and Epigenetic Down-regulation of MicroRNA-212 Promotes Colorectal Tumor Metastasis via Dysregulation of MnSOD
Xiangqi Meng et al.
GASTROENTEROLOGY (2013)
MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis
Keun Hur et al.
GUT (2013)
Activated tumor-infiltrating CD4+regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer
Alexander Pedroza-Gonzalez et al.
HEPATOLOGY (2013)
Recruitment of a Myeloid Cell Subset (CD11b/Gr1mid) via CCL2/CCR2 Promotes the Development of Colorectal Cancer Liver Metastasis
Lei Zhao et al.
HEPATOLOGY (2013)
MicroRNA-195 Suppresses Angiogenesis and Metastasis of Hepatocellular Carcinoma by Inhibiting the Expression of VEGF, VAV2, and CDC42
Ruizhi Wang et al.
HEPATOLOGY (2013)
Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells
Hui-Jye Chen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Metastasis-associated PRL-3 induces EGFR activation and addiction in cancer cells
Abdul Qader Omer Al-aidaroos et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer
Rene Jackstadt et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis
Jiao Zheng et al.
MOLECULAR CANCER (2013)
Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial
Bernard Nordlinger et al.
LANCET ONCOLOGY (2013)
Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment
Noriho Iida et al.
SCIENCE (2013)
The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide
Sophie Viaud et al.
SCIENCE (2013)
The TGFbeta Superfamily Signaling Pathway
Alexander Weiss et al.
WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2013)
Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression
Emily L. Paterson et al.
NEOPLASIA (2013)
Hepatic metastases of colorectal cancer are rather homogeneous but differ from primary lesions in terms of immune cell infiltration
Niels Halama et al.
ONCOIMMUNOLOGY (2013)
miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer
J. Zhang et al.
BRITISH JOURNAL OF CANCER (2012)
Cancer Statistics, 2012
Rebecca Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2012)
Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation
Alexandre Calon et al.
CANCER CELL (2012)
Serum microRNA-29a is a promising novel marker for early detection of colorectal liver metastasis
Long-gang Wang et al.
CANCER EPIDEMIOLOGY (2012)
Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer
Kristoffer Watten Brudvik et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4
Hsin-Yi Chen et al.
CANCER RESEARCH (2012)
A Phase I First-in-Human Study of TRC105 (Anti-Endoglin Antibody) in Patients with Advanced Cancer
Lee S. Rosen et al.
CLINICAL CANCER RESEARCH (2012)
Phosphatase of regenerating liver-3 promotes migration and invasion by upregulating matrix metalloproteinases-7 in human colorectal cancer cells
Su-Kyung Lee et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer
Lixin Ma et al.
INVESTIGATIONAL NEW DRUGS (2012)
Phase III Trial of Cetuximab With Continuous or Intermittent Fluorouracil, Leucovorin, and Oxaliplatin (Nordic FLOX) Versus FLOX Alone in First-Line Treatment of Metastatic Colorectal Cancer: The NORDIC-VII Study
Kjell Magne Tveit et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
The developing cancer stem-cell model: clinical challenges and opportunities
Louis Vermeulen et al.
LANCET ONCOLOGY (2012)
TGFβ signalling in context
Joan Massague
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas
Arnout G. Schepers et al.
SCIENCE (2012)
Systemic shRNA mediated knock-down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation
Mathias Dahlmann et al.
ONCOTARGET (2012)
Targeting MET in cancer: rationale and progress
Ermanno Gherardi et al.
NATURE REVIEWS CANCER (2012)
Outcome After Laparoscopic Radiofrequency Ablation of Technically Resectable Colorectal Liver Metastases
Chet W. Hammill et al.
ANNALS OF SURGICAL ONCOLOGY (2011)
Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles
Chao Wang et al.
BIOMATERIALS (2011)
Global Cancer Statistics
Ahmedin Jemal et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling
Masahiro Sonoshita et al.
CANCER CELL (2011)
LIN28B Promotes Colon Cancer Progression and Metastasis
Catrina E. King et al.
CANCER RESEARCH (2011)
LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases β1 Integrin-Mediated Cell Adhesion and Liver Metastasis
Rich Y. C. Hsu et al.
CANCER RESEARCH (2011)
Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1α
Florian Schelter et al.
CLINICAL & EXPERIMENTAL METASTASIS (2011)
APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis
Qingqing Ding et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation Status
Eric Van Cutsem et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Quantitative Phospho-Proteomic Profiling of Hepatocyte Growth Factor (HGF)-MET Signaling in Colorectal Cancer
Shawna L. Organ et al.
JOURNAL OF PROTEOME RESEARCH (2011)
L1 Cell Adhesion Molecule Is a Novel Therapeutic Target in Intrahepatic Cholangiocarcinoma
Jeong-Ki Min et al.
CLINICAL CANCER RESEARCH (2010)
DOSE-ESCALATION STUDY OF SINGLE-FRACTION STEREOTACTIC BODY RADIOTHERAPY FOR LIVER MALIGNANCIES
Karyn A. Goodman et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2010)
Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator
Florian Schroetzlmair et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
Gunnar Folprecht et al.
LANCET ONCOLOGY (2010)
Singlet oxygen-induced apoptosis of cancer cells using upconversion fluorescent nanoparticles as a carrier of photosensitizer
Huichen Guo et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2010)
Clinicopathological and Prognostic Value of MicroRNA-21 and MicroRNA-155 in Colorectal Cancer
Hajime Shibuya et al.
ONCOLOGY (2010)
Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation
Kajsa Ericson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model
Takanori Kitamura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Commentary: Radiofrequency ablation for colorectal liver metastases: do not blame the biology when it is the technology
Eddie K. Abdalla
AMERICAN JOURNAL OF SURGERY (2009)
T Cell Infiltrate Predicts Long-Term Survival Following Resection of Colorectal Cancer Liver Metastases
Steven C. Katz et al.
ANNALS OF SURGICAL ONCOLOGY (2009)
Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial
A. Okines et al.
BRITISH JOURNAL OF CANCER (2009)
HGF/Met signalling promotes PGE2 biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells
Amy E. Moore et al.
CARCINOGENESIS (2009)
Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer
Carsten Bokemeyer et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
Ulrike Stein et al.
NATURE MEDICINE (2009)
Investigation of water-soluble x-ray luminescence nanoparticles for photodynamic activation
Yuanfang Liu et al.
APPLIED PHYSICS LETTERS (2008)
Inhibition of STAT3(Tyr705) phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells
Shujie Zhao et al.
CANCER RESEARCH (2008)
TSU68 Prevents Liver Metastasis of Colon Cancer Xenografts by Modulating the Premetastatic Niche
Masayoshi Yamamoto et al.
CANCER RESEARCH (2008)
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
Sun-Mi Park et al.
GENES & DEVELOPMENT (2008)
Nanoparticle Self-Lighting Photodynarnic Therapy for Cancer Treatment
Wei Chen
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2008)
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer:: A randomized phase III study
Leonard B. Saltz et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers
Jianbo Wang et al.
MOLECULAR CANCER THERAPEUTICS (2008)
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
Ron Firestein et al.
NATURE (2008)
Cancer-related inflammation
Alberto Mantovani et al.
NATURE (2008)
Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis
Piotr G. Rychahou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
I. A. Asangani et al.
ONCOGENE (2008)
Functional control by codon bias in magnetic bacteria
Megha Sharma et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2008)
Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling
Charlotte Kopitz et al.
CANCER RESEARCH (2007)
Human tumor-derived exosomes selectively impair lymphocyte responses to interieukin-2
Aled Clayton et al.
CANCER RESEARCH (2007)
Let-7 expression defines two differentiation stages of cancer
Scott Shell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer:: The Gruppo Oncologico Nord Ovest
Alfredo Falcone et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
SMAD4-deficient intestinal tumors recruit CCR1(+) myeloid cells that promote invasion
Takanori Kitamura et al.
NATURE GENETICS (2007)
PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo.
Ke Goo et al.
CANCER RESEARCH (2006)
Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development
Liam M. Casey et al.
DEVELOPMENTAL DYNAMICS (2006)
CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer
DZ Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Using nanoparticles to enable simultaneous radiation and photodynamic therapies for cancer treatment
W Chen et al.
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2006)
Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition
HY Irie et al.
JOURNAL OF CELL BIOLOGY (2005)
A Phase I trial of stereotactic body radiation therapy (SBRT) for liver metastases
TE Schefter et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: Role in immune escape
V Huber et al.
GASTROENTEROLOGY (2005)
Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor
TW Bauer et al.
ANNALS OF SURGERY (2005)
Compromised lymphocytes infiltrate hepatocellular carcinoma: The role of T-regulatory cells
E Unitt et al.
HEPATOLOGY (2005)
Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer
CC Schimanski et al.
CLINICAL CANCER RESEARCH (2005)
Global cancer statistics, 2002
DM Parkin et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2005)
Integration of TGF-β/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
J Zavadil et al.
EMBO JOURNAL (2004)
Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors
R Pai et al.
FASEB JOURNAL (2003)
Hepatocyte growth factor signaling regulates transactivation of genes belonging to the plasminogen activation system via hypoxia inducible factor-1
L Tacchini et al.
EXPERIMENTAL CELL RESEARCH (2003)
Scatter-factor and semaphorin receptors: Cell signalling for invasive growth
L Trusolino et al.
NATURE REVIEWS CANCER (2002)
Expression of S100A6 and S100A4 in matched samples of human colorectal mucosa, primary colorectal adenocarcinomas and liver metastases
K Komatsu et al.
ONCOLOGY (2002)
A phosphatase associated with metastasis of colorectal cancer
S Saha et al.
SCIENCE (2001)
Increased expression of S100A6 at the invading fronts of the primary lesion and liver metastasis in patients with colorectal adenocarcinoma
K Komatsu et al.
BRITISH JOURNAL OF CANCER (2000)