Journal
CHEMISTRYSELECT
Volume 1, Issue 8, Pages 1641-1649Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.201600249
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Funding
- University of Reading
- University of Reading (EPSRC-Doctoral Training Grant)
- Gnosys Global Ltd
- Engineering and Physical Sciences Research Council [1402747] Funding Source: researchfish
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A novel series of low molecular weight non-peptidic, biocompatible super-hydrogelators with both water purification and drug delivery properties have been developed. Linking the bis aromatic urea groups responsible for gelation together to form bi- and tri-armed gelators, affords good control over gelation and water purification properties. The use of the gels as effective drug scavengers and delivery systems has been dem-onstrated with dye substrates, via pH inversion, as monitored by UV-vis spectroscopy. Finally, the systems' abilities as both drug scavenging and delivery systems have been demonstrated with the clinically-approved drugs chlorpromazine and doxorubicin, respectively.
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