4.1 Article

Tel:+82-2-880-1298, Fax:+82-2-876-7610

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

An early endothelial cell-specific requirement for Glut1 is revealed in Glut1 deficiency syndrome model mice

Maoxue Tang et al.

Summary: Glut1 plays a crucial role in brain angiogenesis through its cell-autonomous function in brain microvascular endothelial cells. Depletion of Glut1 leads to neuroinflammation, reduced BDNF levels, and disease manifestation, with the most severe effects observed when Glut1 scarcity is induced during neonatal brain angiogenesis. Targeting brain endothelial cells during early development is essential for maintaining proper brain angiogenesis and preventing neuroinflammation in Glut1 deficiency syndrome.

JCI INSIGHT (2021)

Article Neurosciences

Wnt/β-Catenin Signaling Promotes Differentiation of Ischemia-Activated Adult Neural Stem/Progenitor Cells to Neuronal Precursors

Jan Kriska et al.

Summary: The study investigated the impact of the Wnt signaling pathway on regenerative processes in adult mouse brains, revealing that Wnt signaling enhances the regeneration of NS/PCs, promoting their differentiation into neurons and supporting neuronal differentiation in the SVZ.

FRONTIERS IN NEUROSCIENCE (2021)

Review Biotechnology & Applied Microbiology

Review on the Vascularization of Organoids and Organoids-on-a-Chip

Xingli Zhao et al.

Summary: The use of human cells for constructing 3D organ models in vitro has become more popular, but these organoids face challenges in forming complex vascular networks. Organoids-on-a-chip offer a more controllable platform for co-culturing different cells and tissues, but still struggle with simulating signal communications between bionic microenvironments and multiple organs.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Article Cell & Tissue Engineering

Vascularization of human brain organoids

Takeshi K. Matsui et al.

Summary: Human brain organoids are three-dimensional tissues generated in vitro that lack vasculature. Efforts to vascularize brain organoids include adjusting cultivation protocols, utilizing microfluidic devices, and transplanting organoids into immunodeficient mice to promote their development and function.

STEM CELLS (2021)

Review Neurosciences

The Neurovascular Unit: Effects of Brain Insults During the Perinatal Period

Alexander H. Bell et al.

FRONTIERS IN NEUROSCIENCE (2020)

Article Biochemistry & Molecular Biology

Vascularized human cortical organoids (vOrganoids) model cortical development in vivo

Yingchao Shi et al.

PLOS BIOLOGY (2020)

Review Cell & Tissue Engineering

Paracrine Mechanisms of Mesenchymal Stromal Cells in Angiogenesis

Selma Maacha et al.

STEM CELLS INTERNATIONAL (2020)

Review Developmental Biology

Brain organoids: advances, applications and challenges

Xuyu Qian et al.

DEVELOPMENT (2019)

Review Neurosciences

Blood Vessels as Regulators of Neural Stem Cell Properties

Andromachi Karakatsani et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)

Review Cell & Tissue Engineering

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

Timo Rademakers et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2019)

Article Biochemical Research Methods

Engineering of human brain organoids with a functional vascular-like system

Bilal Cakir et al.

NATURE METHODS (2019)

Review Neurosciences

Mouse vs man: Organoid models of brain development & disease

Jonothon J. Marshall et al.

BRAIN RESEARCH (2019)

Article Biotechnology & Applied Microbiology

An in vivo model of functional and vascularized human brain organoids

Abed AlFatah Mansour et al.

NATURE BIOTECHNOLOGY (2018)

Article Neurosciences

Generation of human vascularized brain organoids

Missy T. Pham et al.

NEUROREPORT (2018)

Article Biochemical Research Methods

Generation and assembly of human brain region-specific three-dimensional cultures

Steven A. Sloan et al.

NATURE PROTOCOLS (2018)

Article Engineering, Biomedical

High-throughput fabrication of vascularized spheroids for bioprinting

Lise De Moor et al.

BIOFABRICATION (2018)

Review Biochemistry & Molecular Biology

Modeling Development and Disease with Organoids

Hans Clevers

Article Cell & Tissue Engineering

Role of VEGF-A in angiogenesis promoted by umbilical cord-derived mesenchymal stromal/stem cells: in vitro study

Irina Arutyunyan et al.

STEM CELL RESEARCH & THERAPY (2016)

Article Biochemistry & Molecular Biology

Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro

Maximilian Heiss et al.

FASEB JOURNAL (2015)

Article Developmental Biology

The vascular niche in adult neurogenesis

Tamar Licht et al.

MECHANISMS OF DEVELOPMENT (2015)

Review Physiology

The neurovascular unit - concept review

V. Muoio et al.

ACTA PHYSIOLOGICA (2014)

Article Biochemical Research Methods

Generation of cerebral organoids from human pluripotent stem cells

Madeline A. Lancaster et al.

NATURE PROTOCOLS (2014)

Article Multidisciplinary Sciences

Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster et al.

NATURE (2013)

Review Neurosciences

Wnt Signaling in Vertebrate Neural Development and Function

Kimberly A. Mulligan et al.

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2012)

Article Biochemistry & Molecular Biology

Wnt/β-catenin signaling in cerebral cortical development

Anjen Chenn

Organogenesis (2010)

Article Multidisciplinary Sciences

Wnt/β-catenin signaling is required for CNS, but not non-CNS, angiogenesis

Richard Daneman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Cell & Tissue Engineering

Endogenous Wnt Signaling Maintains Neural Progenitor Cell Potency

Eric M. Wexler et al.

STEM CELLS (2009)

Article Cell & Tissue Engineering

A specialized vascular niche for adult neural stem cells

Masoud Tavazoie et al.

CELL STEM CELL (2008)