Kinetic and inhibition effect studies of ecofriendly synthesized silver nanoparticles on lactate dehydrogenase and ferritin activity of waxy crude oil

The present work investigates the synthesis of silver nanoparticles by biological method using Myrtus communis leaves extract and silver nitrate as precursors. Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR) were used in addition to UV-visible spectroscopy (UV) in order to characterize the AgNPs. The biosynthesized AgNPs exhibited inhibitory effects on ferritin and lactate dehydrogenase activity in sera of covid19 patients compared with control subjects. Kinetic studies of ferritin and lactate dehydrogenase were performed. Further studies on other biological activities were required to exploit AgNPs full potential. Conclusion of this study is prepared using simple, cheap and environmentally green method to synthesis silver nanoparticles. This stage is more suited to large-scale manufacturing since it is speedy and removes the complex steps in other biobased methods (by using fungi and bacteria).

Automated summary

This study investigates the synthesis of silver nanoparticles using a biological method and characterizes the nanoparticles using various techniques. The biosynthesized silver nanoparticles showed inhibitory effects on ferritin and lactate dehydrogenase activity in the sera of COVID-19 patients.