4.5 Article

Residual based attention-Unet combing DAC and RMP modules for automatic liver tumor segmentation in CT

Journal

MATHEMATICAL BIOSCIENCES AND ENGINEERING
Volume 19, Issue 5, Pages 4703-4718

Publisher

AMER INST MATHEMATICAL SCIENCES-AIMS
DOI: 10.3934/mbe.2022219

Keywords

liver tumor; segmentation; CT; residual; attention

Funding

  1. National Natural Science Foundation of China [61741106]
  2. Heilongjiang Provincial Natural Science Foundation of China [LH2019F023]

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This study proposes a new end-to-end network called ResCEAttUnet to improve the segmentation accuracy of liver tumors from CT images. The experimental results demonstrate the significant improvement in segmentation accuracy compared to state-of-the-art methods, indicating the promising potential of the proposed method.
Purpose: Due to the complex distribution of liver tumors in the abdomen, the accuracy of liver tumor segmentation cannot meet the needs of clinical assistance yet. This paper aims to propose a new end-to-end network to improve the segmentation accuracy of liver tumors from CT. Method: We proposed a hybrid network, leveraging the residual block, the context encoder (CE), and the Attention-Unet, called ResCEAttUnet. The CE comprises a dense atrous convolution (DAC) module and a residual multi-kernel pooling (RMP) module. The DAC module ensures the network derives high-level semantic information and minimizes detailed information loss. The RMP module improves the ability of the network to extract multi-scale features. Moreover, a hybrid loss function based on cross-entropy and Tversky loss function is employed to distribute the weights of the two-loss parts through training iterations. Results: We evaluated the proposed method in LiTS17 and 3DIRCADb databases. It significantly improved the segmentation accuracy compared to state-of-the-art methods. Conclusions: Experimental results demonstrate the satisfying effects of the proposed method through both quantitative and qualitative analyses, thus proving a promising tool in liver tumor segmentation.

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