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Novel Findings regarding the Bioactivity of the Natural Blue Pigment Genipin in Human Diseases

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Publisher

MDPI
DOI: 10.3390/ijms23020902

Keywords

genipin; blue colorant; biological activity; safety

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Genipin, an important compound isolated from Gardenia jasminoides and Genipa americana fruits, has various potential therapeutic properties and industrial applications.
Genipin is an important monoterpene iridoid compound isolated from Gardenia jasminoides J.Ellis fruits and from Genipa americana fruits, or genipap. It is a precursor of a blue pigment which may be attractive alternative to existing food dyes and it possesses various potential therapeutic properties such as anti-cancer, anti-diabetic and hepatoprotective activity. Biomedical studies also show that genipin may act as a neuroprotective drug. This review describes new aspects of the bioactivity of genipin against various diseases, as well as its toxicity and industrial applications, and presents its potential mechanism of action.

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