Boosters reduce in-hospital mortality in patients with COVID-19: An observational cohort analysis

Article Medicine, General & Internal

Waning Immunity after the BNT162b2 Vaccine in Israel

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Summary: The immunity against the delta variant of SARS-CoV-2 waned in all age groups in Israel a few months after receiving the second dose of the vaccine, leading to an increase in infection and severe cases.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

Waning Immune Humoral Response to BNT162b2 Covid-19 Vaccine over 6 Months

Einav G. Levin et al.

Summary: A study in Israel revealed that waning immunity after receiving two doses of the BNT162b2 vaccine led to an increase in the incidence of SARS-CoV-2 infection. Levels of spike-binding IgG and neutralizing antibodies decreased more significantly in men, individuals aged 65 or older, and immunosuppressed individuals in a longitudinal study involving nearly 4000 healthcare workers.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Letter Medicine, General & Internal

Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients

Brian J. Boyarsky et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Letter Medicine, General & Internal

Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants

Laith J. Abu-Raddad et al.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Letter Medicine, General & Internal

Early Evidence of the Effect of SARS-CoV-2 Vaccine at One Medical Center

William Daniel et al.

Summary: Following the rollout of mRNA SARS-CoV-2 vaccines under emergency use authorization, there was a significant decrease in the incidence of SARS-CoV-2 infections among health care workers at the University of Texas Southwestern Medical Center.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Infectious Diseases

Outcomes Among Patients with Breakthrough SARS-CoV-2 Infection After Vaccination

Adeel A. Butt et al.

Summary: The risk of developing severe disease or death after breakthrough SARS-CoV-2 infection is higher in older individuals, but lower in those who have been vaccinated. The presence of comorbidities does not affect the severity of disease or death in breakthrough infections.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Letter Medicine, General & Internal

SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness

Aziz Sheikh et al.

LANCET (2021)

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Letter Medicine, General & Internal

Three Doses of an mRNA Covid-19 Vaccine in Solid-Organ Transplant Recipients

Nassim Kamar et al.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel

Yinon M. Bar-On et al.

Summary: After receiving a third dose of the BNT162b2 mRNA vaccine, Israeli residents aged 60 and above who had previously received two doses of the vaccine saw significantly lower rates of confirmed Covid-19 infection and severe illness compared to those who did not receive a booster shot, indicating the effectiveness of the booster dose in reducing infection and severe illness.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers

Moriah Bergwerk et al.

Summary: Among fully vaccinated health care workers, breakthrough infections with SARS-CoV-2 were correlated with neutralizing antibody titers during the peri-infection period. Most breakthrough infections were mild or asymptomatic, although persistent symptoms did occur.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

First Case of 2019 Novel Coronavirus in the United States

Michelle L. Holshue et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Health Care Sciences & Services

Identifying Increased Risk of Readmission and In-hospital Mortality Using Hospital Administrative Data The AHRQ Elixhauser Comorbidity Index

Brian J. Moore et al.

MEDICAL CARE (2017)

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Boosters reduce in-hospital mortality in patients with COVID-19: An observational cohort analysis

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