Evaluation of predictor factors of psychological distress in women with unexplained infertility

Objective: The objective of this study was to establish the frequency of anxiety and depressive symptoms among women diagnosed with unexplained infertility and to identify risk factors. Methods: We conducted a descriptive cross-sectional study. Forty-two women from the CHU de Quebec fertility clinic were recruited. Women completed the 'Hospital Anxiety and Depression Scale' (HADS) self-administered questionnaire, used to estimate prevalence of anxiety and depressive symptoms (score >= 8). Results: Overall, 55% (n=23) of participants were identified with anxiety or depressive symptoms according to the HADS questionnaire. Anxiety symptoms were more frequent (55%1 compared with depressive symptoms (10%). According to a logistic regression model, being under 35years old [odds ratio (OR)=16.6, confidence interval (CI): 1.9-25.0], never had a previous spontaneous abortion (OR= 5.6, CI: 1.1-43.5) and never sought fertility treatment (OR= 5.5, CI: 1.1-45.4) were associated with a higher risk of anxiety and depressive symptoms. Conclusion: Anxiety and depressive symptoms are common among women with unexplained infertility, and strategies should be developed to better support and treat this high-risk population.

Automated summary

This study aimed to determine the frequency of anxiety and depressive symptoms among women diagnosed with unexplained infertility and identify associated risk factors. The results showed that anxiety and depressive symptoms were common among these women, with anxiety symptoms being more frequent than depressive symptoms. Factors such as age under 35, no history of previous spontaneous abortion, and never seeking fertility treatment were associated with a higher risk of anxiety and depressive symptoms.